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Principal Scientist LCMS
Oakland, CAMarch 29th, 2026
Employment Type: Full-timeAvailable Positions: 1Location: On-SiteApplication Deadline: Dec 22, 2025SummaryThe LCMS Principal Scientist will be responsible for supporting non-GLP, GLP (non-clinical), and GCLP (clinical) projects. The role is responsible for supporting lab operations in a non-GLP area.Key ActivitiesIndependently conduct LC-MS method development for biologics (e.g., ADC, mAb, protein, peptide, oligonucleotide, etc.) in support of developability assessment, comparability assessment, in-depth characterisation, biotransformation, and CQA-related analysis.Present and interpret data internally and/or externally as needed.Serve as Subject Matter Expert (SME) for the LCMS platform.Serve as the Principal Investigator responsible for interaction with the client from the study design to scheduling, conducting, reporting, and transferring data. Ensure responsiveness to the client, timely delivery, and overall customer satisfaction.Provide oversight of the laboratory, mentor junior staff, and collaborate to keep improving operational excellence.Assist in establishing and improving policies, procedures, work instructions and SOPs.Understand and adhere to corporate standards regarding code of conduct and Environmental Health & Safety (EHS).Perform other related duties as assigned.Preferred Skills Supervisory experience in both project and talent (people) management is preferred.Ability to work independently and pay close attention to details.Educations & ExperiencePhD, M.S., in Chemistry, Biochemistry or related scientific fields required, including a minimum of 4+(Ph.D.) or 9+ (Master’s) years of CRO/Pharma/Biotech experience.Hands-on experience with high-resolution LCMS method development and in-depth characterization.Are you looking for your next opportunity? We can help. Finding a great opportunity that fosters growth, a great culture, and leadership opportunities can be difficult. Top Quality Recruitment (TQR) connects professionals with leadership opportunities across the Packaging, Food and Beverage, Medical Devices, and Biotechnology industries. With 50+ years of experience, we believe in one-to-one communication and finding the best candidate/employer match possible.TQR is an equal-opportunity employer that encourages diversity. We will consider all applications.Accommodation for applicants with disabilities is available upon request.Are you looking to hire? Get started here:https://www.topqualityrecruitment.com/fill-a-position/See hiring advice: https://www.topqualityrecruitment.com/blog/See all available opportunities: https://www.topqualityrecruitment.com/jobs/We thank all applicants for their interest and appreciate the time and effort involved; however, due to the large volume of resumes received only those candidates selected for an interview will be contacted. Please attached your resume to your application. Job ID: 8083
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