Medical Director - I&I Clinical Development (South San Francisco)

An emerging, pre-IPO biotech in South San Francisco focused on advancing a first-in-class therapeutic platform with the potential to unlock previously intractable targets is growing their clinical development team. As multiple programs move into the clinic, the team is seeking a Medical Director to help lead FIH and early-phase studies. Experience in inflammatory or autoimmune diseases preferred.This is a high-impact role for a physician who wants to shape early clinical strategy and operational execution, work closely with cross-functional teams, and help bring novel therapies into the clinic.South San Francisco, CA - Hybrid Remote FlexibilityWhy This RoleFirst-in-class science with a novel approach to protein degradationMultiple programs approaching FIHOpportunity to own meaningful pieces of early clinical developmentBacked by strong funding with a deep, innovative pipelineWhat You'll DoHelp drive first-in-human and early-phase clinical trials from startup through readoutProvide clinical insight and safety perspective on emerging dataPartner closely with CROs and internal teams to ensure high-quality study executionContribute to dose-escalation decisions, data interpretation, and key clinical deliverablesEngage with investigators and support study-level strategy and executionAdditional responsibilities as neededWhat We're Looking ForMD with biotech/pharma experienceBackground in early-phase clinical development (Phase 1 or 2)Interest in novel mechanisms and innovative scienceCollaborative, hands-on, and motivated by impact in a small-team environmentBackground in inflammatory, autoimmune, allergy, or endocrine-related diseases a plus