Scientist - Oncology (Targeted Protein Degradation)

POSITION SUMMARY: The candidate will join the Oncology team, focusing on innovative cell biology techniques to support early drug discovery. The ideal candidate will have strong technical skills, clear communication abilities, and a desire to contribute to cutting-edge research in the field of Oncology and targeted protein degradation. ESSENTIAL DUTIES AND RESPONSIBILITIES: Perform the full spectrum of laboratory activities and develop, troubleshoot, and optimize cell-based and biochemical assays in support of target validation, drug discovery & development efforts. Independently develop proposals and implement assays for assessment of potency, target engagement, and mechanism of action of novel compounds using multiple techniques (measuring cell growth, density, viability; measuring protein levels; and preparing samples for downstream analysis, e.g., proteomics). Maintain laboratory records and notebook, analyze and interpret experimental data, summarize results, and propose follow-up experiments to test biological hypotheses. Collaborate with colleagues in other functional areas to design experiments for target validation, selectivity assessments, mechanism of action studies, and biomarker discovery. Engage in scientific discussions and share ideas with an internal team of cross-functional biologists and proteomic scientists. Handle laboratory workflows and participate in project/timeline management. Mentor and assist junior team members. Increase BPGbio’s visibility within the scientific community through publications and conference presentations. Other duties as assigned REQUIREMENTS: Requires a Ph.D. degree in cancer biology, cell biology, biochemistry or related discipline with 0-5 years of relevant post PhD experience. Experience with method development applying to targeted protein degradation, ubiquitin-proteasome system biology, functional proteomics technologies, and oncology research. In-depth knowledge and hands-on experience with molecular and cellular biology. Proficient in molecular and immunological assays (ELISA, WB, FACS, etc.). Ability to handle multiple projects and work in a fast-paced dynamic team environment. Solid scientific training/productivity as identified through high-impact publications demonstrating creative thinking as well as innovative technical approaches. Excellent oral and written communication skills and a proven ability to prepare manuscripts for presentation and publication is required. Excellent data organization and strong critical thinking, decision-making, and problem-solving aptitudes. Demonstrated ability to work in a dynamic environment as a team player with a strong work ethic, excellent communication, and time management skills.