Principal Mechanical Engineer II, Early Research and Development

Senior Mechanical EngineerA Medical Device Manufacturing / Pharmaceutical client of Sharp Decisions is seeking a Senior Mechanical Engineer in Santa Clara, CA. This is a 6-month contract with possible extension, offering $79.45/hour on a W2.Job DescriptionThis is a hands-on role for a multidisciplinary expert focused on solving core mechanical challenges for next-generation platforms. The role involves designing, building, and testing innovative electro-mechanical, pneumatic, thermal, and fluidic solutions to ensure system performance, reliability, and longevity.The Principal Mechanical Engineer will drive innovation for next-generation instrumentation, requiring high motivation, independence, and resourcefulness in a fast-paced, collaborative environment.Core ResponsibilitiesLead end-to-end mechanical design and development of electro-mechanical, pneumatic, fluidic, and thermal sub-systems.Collaborate with cross-functional engineering teams to define and manage technical interfaces.Develop mechanisms for automated reagent and flow cell loading, clamping, and sealing.Design and integrate thermal control systems including heating/cooling elements and sensors.Partner with simulation teams to validate CFD, thermal, and optical models.Serve as technical expert during system integration, verification, and troubleshooting.Lead cross-functional design reviews and resolve technical trade-offs.Manage timelines and deliverables for mechanical sub-systems.Create and maintain detailed CAD models, drawings, and specifications.Contribute to system architecture and technical strategy.Present technical progress and engineering decisions to stakeholders.Required QualificationsPhD with 3+ years, Master's with 4+ years, or Bachelor's with 7+ years of relevant experience.Hands-on expertise in mechanical, electro-mechanical, and pneumatic system design.Experience in thermal management and precision temperature control systems.Experience with fluidics systems (pumps, valves, tubing, sensors).Proficiency in 3D CAD tools (e.g., SolidWorks).Experience with manufacturing processes (machining, injection molding, 3D printing).Strong troubleshooting skills across hardware, software, and chemistry interfaces.Experience with machine shop tools and rapid prototyping technologies.Proficiency in Python, LabVIEW, or similar tools for device control and data acquisition.Preferred QualificationsExperience leading technical projects and mentoring engineers.Experience with simulation tools such as CFD and FEA.Experience with next-generation sequencing (NGS) or genomics instrumentation.Experience in regulated product development environments.Strong communication and interpersonal skills.Ability to manage multiple priorities in a fast-paced environment.2