Scientist I, Immuno-Oncology & Cell Therapy *PC

Description Your Role: As a member of the Research and Development team, you will have the opportunity to play a key, hands on role in performing scientific experiments that lead to the next generation of cell and gene therapies. You will be responsible for human immune cell isolation and culture, tumor cell line culture and maintenance, carrying out advanced methods of T cell activity analysis, and using gene transfer techniques including lentiviral gene vector design and LNP-based gene delivery. You will also work with hematopoietic stem cells (HSCs) and implement new ways to use these cells in gene therapy approaches. These research and development pathways utilize new and innovative technologies developed in-house, such as advanced flow cytometry, imaging, automated cell processing in static and active cultures, and translating lab-scale innovation to clinical systems such as the CliniMACS Prodigy. Our core strength is lentiviral and LPN-based gene vector development. The incumbent will have the opportunity to interact with a highly diverse and collaborative team of scientists focused on research and development of novel cell and gene therapies, to contribute to scientific publications, development of clinic-ready and commercial cell therapy products, and to grow professionally. Essential Duties and Responsibilities: Culture and maintenance of primary human immune cells, leukemia and lymphoma cell lines, and cancer cell lines. Employ state of the art immune cell functional assays including flow cytometry, cytolytic and cytokine secretion analysis, metabolic assays, cell avidity measurement, and gene expression analysis. Isolation, culture and gene modification of HSCs. Employ novel gene vector and LNP-based gene modification. Experience in lentiviral gene vectors is a plus. Work independently and in a team environment, effectively communicating results featuring precise data analytics. Other duties as assigned. Requirements PhD or MD, preferably with a postdoctoral training and strong expertise in immunology, gene vector biology, cell isolation and expansion techniques. Cell culture and flow cytometry experience. Expertise in hematopoietic stem cell culture and gene engineering. Familiarity with CAR-T cells. Familiarity with DNA sequence databases, flow cytometry software, statistical software packages for data analysis and presentation. You are creative, goal-oriented and able to work both in independent and multidisciplinary situations. In addition, you welcome new challenges. Excellent communication skills and a proven track record in preparing scientific data for presentation. Physical Demands: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to walk; use hands and fingers, handle, or feel; reach with hands and arms, talk, and hear. The employee is required to stand; climb or balance and stoop, kneel, or crouch. The employee must occasionally lift and/or move up to 25 pounds. Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail. Work Environment: The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. This job is performed in a variety of facilities. Each person performing this job must have a home office environment, which is temperature controlled. This job requires the person to be mobile to visit clinical trial sites. Due to the travel requirements, this position may be exposed to natural elements of nature. Used research/clinical equipment may be handled in this job and strict SOPs must be followed and PPE may be required to be worn per Miltenyi or hospital policies. The hiring range for this position is expected to fall between $86,783 - $102,109/year, reflecting the range candidates can reasonably expect to be considered for at time of offer, based on factors such as experience, internal equity, and qualifications. The salary of the finalist(s) selected for this role will be set based on a variety of considerations, including but not limited to internal equity, experience, education, specialization, skills, abilities, and training. The above range represents the Company's good faith and reasonable estimate of possible compensation at the time of posting. In addition to your salary, the Company offers a comprehensive benefits package, including health, vision, and dental insurance, as well as a 401(k) plan. All benefits are subject to eligibility requirements. Certain positions may also be eligible for additional compensation such as bonuses or commissions. Miltenyi Biotec is an EO Employer - M/F/Veteran/Disability/Sexual Orientation/Gender Identity Miltenyi Biotec, Inc. participates in E-Verify. Are you ready to start revolutionizing biomedical research? When you join Miltenyi Biotec, you join a family that is passionate about making a real impact - one breakthrough at a time. For over 30 years, we have played a pivotal role in the design, development, manufacture, and integration of products for sample preparation, cell separation, cell analysis, imaging, and cell culture needs. These developments have led to cutting-edge cell and gene therapies - transformative methods that mobilize the body's own cells and genetic blueprint to tackle diseases such as cancer and autoimmune conditions. Today, our more than 18,000 solutions play a vital role in paving the way for the medicine of tomorrow. Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.