Principal Clinical Scientist

Principal Clinical Scientist (AI Training)About The RoleWhat if your deep expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to frontier AI research — helping ensure that the clinical intelligence built into next-generation AI systems meets the standards expected in real regulatory submissions.This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work at the intersection of medicine and AI — on their own schedule.Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10–40 hours/weekWhat You'll DoDesign and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluationInterpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory expectationsEvaluate AI-generated clinical analyses for scientific soundness and methodological rigorProvide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomesWork independently and asynchronously — fully on your own scheduleWho You AreSenior-level experience designing clinical trial protocols intended for regulatory submissionDeep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent international bodiesStrong grounding in clinical research methodology, biostatistics, or translational scienceNaturally detail-oriented with a systematic, evidence-driven approach to evaluationClear and precise written communicator — able to articulate complex scientific reasoning in structured feedbackNice to HavePrior experience with data annotation, data quality assurance, or evaluation systemsFamiliarity with AI tools or clinical informatics platformsBackground in pharmacology, oncology, rare disease, or another specialist therapeutic areaExperience contributing to regulatory dossiers, CTD submissions, or scientific advisory processesWhy Join UsWork directly on frontier AI systems impacting clinical and biomedical research at a global scaleFully remote and flexible — work when and where it suits youFreelance autonomy with the structure of meaningful, task-based expert workInfluence how AI understands, evaluates, and reasons about real-world clinical evidenceCollaborate with world-leading AI research teams and labsPotential for ongoing work and contract extension as new projects launch