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Global Program Clinical Lead, Oncology (Solid Tumours)
Somerville, MAApril 6th, 2026
The Global Program Clinical Lead, Oncology (Solid Tumours) provides end-to-end medical and clinical leadership for global early development programs across solid tumour indications. This role defines the vision and strategic direction of assigned assets, ensuring a scientifically robust, medically sound development strategy from preclinical stages through early clinical development and transition to late-stage programs.The position is accountable for shaping and executing global clinical strategy, with full decision-making authority for early development programs. It drives cross-functional alignment across research, translational science, regulatory, and clinical operations, while maximizing asset value through target product and value profile development and integration of precision medicine approaches.Key ResponsibilitiesServe as the global clinical lead for early-stage oncology programs, providing strategic medical input into program design, execution, and go/no-go decisions.Define and implement clinical development strategies from preclinical evaluation through Phase I/II trials.Guide preclinical asset development to enable informed decision-making and seamless transition into clinical studies.Collaborate with translational research teams to integrate biomarkers, scientific insights, and precision medicine strategies into clinical plans.Oversee study design, protocol development, medical monitoring, and benefit–risk assessments to ensure high-quality execution and patient safety.Lead cross-functional matrix teams, fostering a culture of ownership, innovation, and peer accountability.Support pipeline expansion by incorporating novel assets through internal and external innovation efforts.Engage with external collaborators, academic partners, key opinion leaders, and regulatory authorities to inform clinical strategy.RequirementsMedical Degree (M.D.) with board certification in Oncology, Hematology, or a related subspecialty.Minimum of 5 years of direct patient care experience in oncology/hematology.5+ years of pharmaceutical or biotech industry experience, including at least 2 years in early drug development.Strong understanding of oncology drug development, including small molecules, biologics, and novel modalities.Demonstrated ability to design and lead early-phase clinical trials.Experience interacting with regulatory authorities (FDA, EMA, etc.) and external collaborators.Exceptional leadership and cross-functional collaboration skills, with a track record of driving strategic impact and fostering innovation.
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