Director, Marketing

Job DescriptionDirector Marketing, GCS KidneyVertex is seeking a talented leader to join our Global Commercial Strategy (GCS) team and work on our Autosomal Dominant Polycystic Kidney Disease (ADPKD) pipeline program. ADPKD is a genetic kidney disease characterized by the growth of kidney cysts that ultimately results in kidney failure and premature mortality.The Director GCS will be responsible for developing commercial strategy, generating new market insights, developing and positioning our brand(s), and preparing for launch. This role will report to the GCS Vice President for Kidney Disease, who leads global commercial strategy for all Vertex Kidney programs. The successful candidate will have a track record of impact in commercial roles, a strong consulting-like skillset, and the ability to thrive in a fast-paced, innovative-focused environment.Key Duties And ResponsibilitiesGenerate Market & Customer InsightLead development of deep HCP, patient, and payer insights across priority geographies through primary and secondary research, advisory boards, and congress engagementContinuously assess the competitive and external landscape in partnership with Competitive IntelligenceRefine understanding of target physicians, treatment centers, and addressable patient populations, including diagnostic and referral pathwaysBuild Early Commercial & Brand StrategyDefine target product profiles (TPPs) and shape early brand positioning and differentiation for pipeline assetsDevelop portfolio strategy, disease education, and diagnostic/awareness strategies, including integration of companion diagnostics (CDx)Partner with HEOR and RWE teams to build a compelling value story for global stakeholdersProvide commercial input into clinical development, including pivotal study design, endpoint selection, and geographic prioritization to optimize future launch successConduct commercial assessments to inform program decisions and investment prioritizationDrive Launch Readiness & Execution PlanningPartner cross-functionally to define global commercialization strategy, including market entry approaches in geographies without an existing footprintSupport global access and pricing strategy, including engagement with EU payer scientific advice processesCollaborate with CDx partners to ensure integrated diagnostic and therapeutic commercialization planningTranslate strategy into clear executional plans, partnering with regions and ensuring alignment with medical, legal, and regulatory requirementsServe as a key commercial voice across clinical, regulatory, research, and commercial teamsShape disease area and portfolio strategy, including lifecycle and future indicationsLead key planning processes including long-range planning, brand planning, and strategic budgetingDrive alignment through clear communication, structured problem-solving, and compelling storytellingKnowledge And SkillsExperience in early asset strategy / pipeline commercialization / launch planningStrong background in strategic planning and structured problem-solving (consulting or equivalent experience is highly valued)Experience with diagnostic testing, companion diagnostics (CDx), or complex patient identification pathways strongly preferredDemonstrated ability to translate scientific data into clear, differentiated brand narratives and strategiesExceptional communication skills, including executive-level storytelling and use of strategic frameworksProven ability to lead cross-functional teams and influence without authority in a matrixed organizationExperience in rare disease, nephrology, or specialty markets preferredEducation And Experience10+ years of experience in biopharma/healthcareBachelors degree requiredAdvanced degree preferred (MBA, PhD, PharmD, MD)Scientific background strongly preferred, with demonstrated ability to engage deeply with clinical and scientific dataPay Range$196,000 - $294,000Disclosure StatementThe range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex DesignationHybrid-Eligible Or On-Site EligibleFlex Eligibility StatusIn this Hybrid-Eligible role, you can choose to be designated as: Hybrid: work remotely up to two days per week; or select On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.Company InformationVertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com