Research Fellow, Radiology Radiochemist

Department:36398 Wake Forest University Health Sciences - Radiology: XrayStatus:Full timeBenefits Eligible:YesHours Per Week:40Schedule Details/Additional Information:M-F 8:00 AM - 5:00 PM. Hours could vary depending on grants workload.Pay Range$30.70 - $46.05Job SummaryThe Radiochemist Postdoctoral Fellow is needed to fasten discovery-to-translation of novel molecular imaging agents by adding dedicated expertise in organic synthesis for radiotracer precursor design, optimization, and scale-relevant chemistry, enabling higher success rates for in vivo imaging studies. This post-doc research fellow will work on to developing, evaluating and designing novel PET imaging radiotracers for neurological disorders in rodent and nonhuman primate models. The candidate will also validate new biological methods to characterize their binding affinity in vivo, ex vivo, and in vitro using established lab protocols and resources.Major tasks/activities will include:Design and multi-step organic synthesis of radiolabeling precursors and reference standardsRadiochemistry translation support (precursor suitability for labeling, stability, impurity risk mitigation, robust chemistry packages for reproducible runs)Method development and documentationSOP drafting, reaction optimization records, analytical methods (HPLC/GC/MS/NMR where applicable), reproducibility packagesCross-functional collaboration with imaging scientists, nuclear medicine/PET operations, and disease-area investigators to move candidates from concept to clinical studiesScholarly productivity & training: manuscripts, abstracts, presentations; mentoring trainees in synthesis/radiochemistry best practices-supporting Radiology's stated commitment to patient-centric care, education, and innovation/research.Key Responsibilities:• Design and synthesize novel ligands for imaging of Alzheimer's disease biomarkers.• Develop and optimize radiolabeling protocols• Perform in vitro and in vivo evaluation of probe specificity, stability, and pharmacokinetics.• Collaborate with neuroscientists, pharmacologists, and imaging specialists.RequirementsPhD in Organic Chemistry, Medicinal Chemistry, Radiochemistry, or Analytical ChemistryEducational expertiseExpert in:Organic synthesis of small molecules, large peptidesHPLC, GC, TLC and NMR characterizationsStrong scientific writing and presentation skillsTroubleshooting in technical aspects of organic and analytical chemistryExperience in handling radioactive materials will be an advantageOur Commitment to You:Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more - so you can live fully at and away from work, including:CompensationBase compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or trainingPremium pay such as shift, on call, and more based on a teammate's jobIncentive pay for select positionsOpportunity for annual increases based on performance Benefits and morePaid Time Off programsHealth and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term DisabilityFlexible Spending Accounts for eligible health care and dependent care expensesFamily benefits such as adoption assistance and paid parental leaveDefined contribution retirement plans with employer match and other financial wellness programsEducational Assistance ProgramAbout Advocate Health