LC-MS/MS Scientist – Method Development & Analytical Testing

*About Ebien Labs* Ebien Labs is an Austin-based clinical laboratory specializing in advanced diagnostic testing. We combine established laboratory science with emerging analytical technologies to expand and improve our testing capabilities. As a growing laboratory, we offer scientists the opportunity to work hands-on with analytical instrumentation, contribute to new method development, and have a direct impact on the expansion of our testing menu. *Overview* We are seeking a hands-on *LC-MS/MS Scientist – Method Development & Analytical Testing* to join our laboratory team in Austin, Texas. The ideal candidate will have practical experience with LC-MS/MS testing and analytical method development, including method optimization, validation/verification, troubleshooting, sample preparation, and data analysis. This position is ideal for someone who enjoys hands-on laboratory work and can take ownership of analytical methods from development through routine testing. *Responsibilities* * Develop, optimize, and troubleshoot quantitative LC-MS/MS methods * Perform method validation and verification studies * Conduct routine LC-MS/MS testing and analyze analytical data * Prepare samples, standards, calibrators, and quality controls * Evaluate method performance, including accuracy, precision, linearity, sensitivity, and reproducibility * Troubleshoot chromatography, mass spectrometry, sample preparation, and method-performance issues * Perform routine instrument maintenance and assist with calibration and troubleshooting * Maintain accurate laboratory records, SOPs, and method-development documentation * Support implementation and transfer of new analytical methods into routine laboratory testing * Follow established laboratory quality and regulatory procedures *Qualifications* * Bachelor's degree in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field * Hands-on experience operating LC-MS/MS instrumentation * Experience with analytical method development, optimization, validation, or verification * Strong understanding of chromatography, mass spectrometry, calibration, and quantitative analysis * Strong troubleshooting and problem-solving skills * Ability to maintain accurate technical documentation * Ability to work independently and collaboratively in a growing laboratory environment *Preferred Qualifications* * 2+ years of hands-on LC-MS/MS experience * Experience developing quantitative LC-MS/MS methods * Experience analyzing biological samples or other complex matrices * Experience working in a clinical, pharmaceutical, biotechnology, or analytical laboratory * Familiarity with regulated laboratory environments and laboratory quality systems *What We're Looking For* We are particularly interested in candidates who have experience beyond simply operating established LC-MS/MS methods. The ideal candidate understands method performance and can independently identify, troubleshoot, and resolve analytical challenges. *Job Type:* Full-time *Pay:* $65,000–$72,000 per year *Location:* Austin, TX 78746 Pay: $65,000.00 - $72,000.00 per year Benefits: * Dental insurance * Health insurance * Life insurance * Paid time off Experience: * Method Development: 1 year (Preferred) * LCMS/MS: 1 year (Preferred) Work Location: In person