Senior Research Associate

About ProximaProxima (formerly VantAI) is advancing an AI-native approach to drug discovery by making protein interactions programmable. Our platform brings together foundation-model machine learning, a scalable data generation engine, and a partnership track record exceeding $5B in collaborations across the world’s leading biopharma and tech organizations. We’ve recently closed an oversubscribed seed round partnering us with an elite group of sophisticated and dedicated VCs including DCVC, Nvidia’s Nventures, AIX, Yosemite among others.Neo-1 is our all-atom foundation model that combines state-of-the-art structure prediction and molecular generation in a single system. Neo-1 enables rapid exploration of chemical and structural space for high value, previously intractable targets, and in particular unlocks small molecule proximity therapeutics like molecular glues with AI for the first time.In parallel, Proxima is developing an advanced structural interactomics platform built on proprietary cross-linking mass spectrometry (XLMS) technology and a lab equipped with next-generation mass spectrometry instrumentation. This platform produces proteome-scale interactome maps and helps identify small molecules that modulate protein interactions. Together with Neo-1, it creates an integrated system capable of co-folding protein complexes while also generating candidate small molecules to influence those interactions.Based on these proprietary capabilities, Proxima is developing a robust pipeline of first-in-class medicines across several therapeutic areas including immunology and inflammation, cardiometabolic and aggregate-driven diseases. The company is currently advancing multiple assets through preclinical development that address both novel and well validated targets.About The RoleWe are seeking a hands-on Contract Senior Research Associate to support cell-based and molecular biology experiments in a fast-paced research environment. This role will focus on executing high-quality lab work, maintaining strong documentation standards, and supporting multiple ongoing projects with minimal supervision.What You’ll DoPerform mammalian cell culture and routine cell-based assays, including viability, proliferation, and apoptosis assaysExecute molecular biology techniques such as PCR, Western blotting, and ELISAMaintain accurate experimental records in compliance with GLP standardsIndependently manage multiple experiments and timelines in a dynamic lab settingTroubleshoot experimental issues and contribute to continuous improvement of lab workflowsCollaborate closely with scientists to support discovery and development effortsMust HavesBachelor’s degree in Biology or a related field2–5 years of hands-on experience with mammalian cell culture and cell-based assays in a drug discovery settingProficiency in core molecular biology techniques including PCR, Western blot, and ELISAStrong troubleshooting skills and experience working under GLP or similar quality standardsAbility to manage multiple projects independently in a fast-paced environmentExcellent organizational skills with strong attention to detail and record keepingNice to HavesExperience with proteomics workflowsExperience generating lentiviral stable cell linesFamiliarity with CRISPR-based gene editing technologiesProficiency with data analysis tools such as GraphPad Prism, ImageJ, or FlowJoBasic statistical analysis skillsPrior pharmaceutical or biotech experience, particularly in drug discovery environmentsExperience with advanced cell culture models, including primary cells or 3D cultures