Chief of Staff to CEO

About the RoleThe Chief of Staff (CoS) will work closely with the CEO, serving as a trusted advisor, gatekeeper, problem solver and strategic partner to develop and implement strategies that advance our mission. It is a fast-track role to become an Executive in the company, and you will be a member of the Executive Team. In this role you will have both internal and external-facing responsibilities, and will provide strategic oversight to operational and communication needs across the company.As the CoS, you will have to handle complex situations and multiple responsibilities simultaneously, mixing long term projects with the urgency of immediate demands. This role is a front seat to all the action in getting a startup off the ground and a terrific opportunity to leverage your broad visibility into the organization to identify challenges, develop solutions, and be an integral part of executing critical workflows. This is an ideal role for a top-performer who thrives at the intersection of strategy and execution, enjoys solving ambiguous problems, and wants accelerated exposure to executive-level decision making.This role is part of the Office of the CEO and will directly manage the current Strategy and Operations team. You'll be onboarding with the current Chief of Staff, and reporting to our CEO once ramped.ResponsibilitiesStrategic Partnership to the CEOServe as a trusted advisor and strategic thought partner, helping the CEO prioritize, sequence, and drive the company's most critical decisionsAct as an extension of the CEO's capacity - amplifying insight, synthesizing information, and ensuring the CEO's time is leveraged for the highest-impact activitiesPrepare executive communications, board narratives, leadership offsites, and strategic briefings.Organizational Alignment & Operating RhythmOwn the company's operating cadence, including Executive Team meetings, quarterly planning, reviews, and cross-functional forumsEnsure organizational alignment on priorities, metrics, and accountability frameworksDrive clarity across teams by translating strategic goals into executable plansDecision Support & Insight Generation* Structure analyses that distill complex data into actionable insights for the CEO and leadership team.* Provide decision support for strategic opportunities, including market assessments, product expansion initiatives, partnership evaluation, or financial modelingIncrease the quality and speed of decision-making across the company through high-quality strategic researchExecution Leadership for Strategy and Operations functionLead and project manage multi-threaded, high-stakes company initiatives that span clinical operations, site network growth, product development, commercial strategy, and people operations.Build frameworks, workflows, and playbooks that improve organizational performance and scaleLead and manage the Strategy and Operations team (currently 1 direct report)Internal and External Communications* Support CEO communication with employees, the Board, investors, partners, and key customersEnsure information flows seamlessly across teams and that the CEO is prepared for all engagementsWhat We're Looking ForRequired Qualifications6-8 years of experience in management consulting, strategy, business operations, or a comparable high-performance environment.Strong business acumen with familiarity in healthcare, life sciences, digital health, or tech-enabled servicesProven ability to structure problems, build analytical frameworks, and generate concise, insight-rich recommendationsExceptional project management skills: ability to run multiple initiatives, align stakeholders, and drive outcomes independentlyStrong executive presence with the ability to earn trust quickly and communicate with clarity and influenceExperience thriving in fast-paced, high-growth, ambiguous environmentsWillingness to be in our NYC or Cambridge office 2+ days per weekWillingness to travel ~15% for customer, partner, or conference engagementPreferred QualificationsExperience in health-tech, clinical research, or AI-driven healthcare solutionsExposure to C-suite advising, board engagement, or executive-level decision supportPrior experience working inside a scaling startup or operator role