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Full-Stack Software Engineer

ZyphraMillbrae, CAMay 19th, 2026
Job Description Zyphra is an artificial intelligence company based in San Francisco, California.The Role:As a Full-Stack Software Engineer, you will be a core contributor to Zyphra's Agentic Systems and Interaction projects. You will be at the forefront of building a next-generation desktop and browser-based agent (end-to-end) that can autonomously navigate the web, interact with filesystems, and complete complex user tasks. This role spans agentic orchestration, frontend interfaces, secure sandboxing environments, large-scale document search and retrieval, and language/vision model integration.You'll Work Across:Design and implementation of different agentic system designs capable of interacting with browsers, operating systems, enterprise filesystems, collaboration tools, etc.Building search and retrieval pipelines across large-scale structured and unstructured dataBuild the backend layer for RAG systems and other information context management systems required for agents to operateIntegrating LLMs, vision models, reinforcement learning, and scaffolding frameworks for autonomous, multi-step decision-makingWhat matters most is your drive to build production-grade softwareWe value velocity and curiosity, especially in fast-moving and ambiguous environmentsWhat We're Looking For / Requirements:Proficiency in Python and a deep understanding of building and debugging complex end-to-end applicationsExperience working with SaaS environment and production workloads, web interfaces, databases, search engines, and queuing systemsExperience developing browser extensions or automation tools with fine-grained control over the browser (mouse, tabs, DOM)Understanding of LLMs, prompting techniques, and orchestration frameworks for multi-step reasoningAbility to work across the whole stack from web interfaces to control plane and data infrastructure like queuing systems, databases, and search indexesExperience designing or working with secure and virtualized execution environmentsExcellent communication and collaboration skills across product, research, and engineering teamsQualifications / Additional Skills:Experience building or integrating retrieval-augmented generation (RAG) systemsExperience working with enterprise security and compliance frameworks (i.e., SOC 2, GDPR, etc.)Familiarity with embeddings, vector databases and large-scale document indexingKnowledge of web automation tools and headless browser environments (i.e., Puppeteer, Playwright)Understanding of sandboxed or containerized compute environments with strict access controlsComfort designing user-facing agentic workflows and reasoning systems that span multiple modalities (text, vision, actions)Experience using and fine-tuning models for screen reading, OCR, or UI understandingBackground in HCI or interest in building intuitive agent interfaces that extend human capabilitiesMachine Learning experience as a double bonusWhy Work at Zyphra:Our research methodology is grounded in methodical, step-by-step approaches to ambitious goals. Both deep research and engineering excellence are equally valuedWe strongly value new and crazy ideas and are very willing to bet big on new ideasWe move as quickly as we can; we aim to minimize the bar to impact as low as possibleWe all enjoy what we do and love discussing AIBenefits and Perks:Comprehensive medical, dental, vision, and FSA plansCompetitive compensation and 401(k) planRelocation and immigration support on a case-by-case basisIn-office snacks and meals providedUnlimited PTO and company holidaysIn-person team in San Francisco with a collaborative, high-energy environment