Lead Full Stack Developer (C#/.NET)

Overview In this role you will lead the design, development and operation of end-to-end web applications and data-driven solutions for clinical trial operations. You’ll be a hands-on technical leader, mentoring peers while delivering scalable, secure front- and back-end components. You’ll work with cross-functional teams to translate complex clinical requirements into practical technical solutions and drive SDLC, GxP, and 21 CFR Part 11 compliant delivery. This role offers high visibility in a mission-driven oncology environment with cloud modernization and platform reliability at its core. Compensation / Benefitsmedical, dental, and vision coveragelife and disability insurancecompany matched 401(k)tuition reimbursementgenerous vacation/sick plansflexible work schedules ResponsibilitiesLead and mentor the application development team while contributing as a hands-on Full Stack DeveloperDesign scalable frontend and backend components, APIs, and UI workflows following clean architectureEmbed security best practices and oversee vulnerability remediation across the SDLCCollaborate with product owners, analysts, PMs, platform engineering and analytics to translate needs into solutionsOwn end-to-end technical solutions: architecture, implementation, testing, deployment and supportEstablish coding standards, automated testing, and CI/CD pipelines to improve quality and release frequencyCoordinate with Solutions Architect, DevOps and Data teams on scalable designsEnsure development adheres to SDLC, GxP, and 21 CFR Part 11 constraintsDesign secure integrations with external clinical and operational systemsTroubleshoot complex issues and lead root cause analysisDrive cloud performance, cost optimization, security posture, and CI/CD automationStay current with AWS Cloud development tools used by the systemsEstimate effort, manage time effectively, and adapt to changing prioritiesPromote documentation and knowledge sharing; conduct design reviews and mentorship Key requirementsMinimum 8 years as a full stack developerMinimum 3 years leading a development team (on-prem and Cloud apps)Core stack: C#/ASP.NET, .NET, Angular, SQL, NoSQL, AWSProficiency in Angular and recent project experienceExperience redeveloping on-prem apps for AWS CloudEnd-to-end cloud software development project leadershipExperience building AWS-based sites, apps, integrationsAWS services: CloudWatch, SES, S3, ECR, ECS, LambdaUI/UX experience with Blazor or AngularRelational and non-relational databasesGitHub and GitHub ActionsDocker container experienceCI/CD pipeline managementPreferred: Terraform, FargateCRO/pharmaceutical environment knowledge, GxP and 21 CFR Part 11 familiarityExperience migrating on-prem data centers to AWSMentorship and leadershipCollaborative cross-functional communicationProblem solving and root cause analysisC#/ASP.NET, .NETAngularSQL and NoSQL databases