Clinical Supply Manager

Company OverviewTango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.Tango’s labs and offices are located at 201 Brookline Avenue, in the vibrant Fenway area of Boston, MassachusettsSummaryWe are seeking a Clinical Supply Manager (CSM) to lead the end-to-end clinical supply management process of our growing clinical portfolio. This role will serve as the primary sponsor contact for external vendors managing the packaging and labeling, storage, distribution, and return/ destruction of clinical supplies.In a fast-paced, small biotech environment, the CSM will plan, execute and oversee clinical supplies in alignment with trial timelines, budget, regulatory requirements and internal standards. This individual will play a key role in enabling clinical trial start, patient enrollment, and continuous supply as per trial requirements, proactively identifying and mitigating risks, and ensuring compliance of clinical supply with applicable regulations and internal standards.The ideal candidate is highly collaborative, detail-oriented, and comfortable operating in a hands-on environment, with a focus on building scalable processes, tools, and best practices to support efficient and compliant clinical trial execution.Your roleDevelop and maintain global clinical supply strategies, including forecasting needs for investigational products, comparators, and co-medicationsOversee inventory levels at depots and clinical sites, defining resupply strategies based on usage trends to prevent shortagesCoordinate distribution, importing, and exporting of materialsEnsure all activities comply with Good Manufacturing Practices (GMP), ICH guidelines, and internal standardsManage external vendors (incl. budget), such as Clinical Manufacturing Organizations (CMO), packaging partners and depotsTrack vendor performance using metrics, KPIs, and KRIsAct as the primary clinical supplies contact for Clinical Trial Teams (CTT), Chemistry, Manufacturing, and Controls (CMC), and quality assurance (QA)Organize and coordinate meetings with key stakeholders, including decision tracking and action item follow-upGenerate optimal distribution plans and develop tools, forms etc. to track and document end-to-end processesTrigger and track shipments of clinical supply from central depot to regional hubs and local depotsContribute to Information Response Technology (IRT) set-up, testing and maintenance in close collaboration with relevant CTT functions to ensure efficiency, timeliness and accuracy of clinical supplies managementProvide input into label text as well as into packaging and labeling materialsIdentify and assesses risks and issues related to clinical supplies, proactively communicate them and lead the development and implementation of mitigation strategies and action plansEnsure inspection and audit readiness of clinical supplies; participate in internal audits and inspection from health authorities, as required.What You Bring5+ years of supply management experience. Experience in leadership preferredBachelor’s degree in Life Sciences, Pharmacy or related fieldExperience working in global clinical development organizationExperience in Oncology development (preferred)Experience in outsourcing and oversightDirect experience with health authority inspections of clinical supply management (preferred)Knowledge of relevant regulations and guidelines (GMP, ICH guidelines, HSE)Knowledge of appropriate supply chain systems used for forecasting and demand planning as well as supply management metrics, KPIs, and KRIsFamiliarity with other systems used in clinical trials (e.g., CTMS, IRT, eTMF)Strong operational excellence with high attention to detailsStrong vendor management and project management skillsLeadership skills with the ability to lead cross-functional teamsStrong interpersonal and communication skillsStrong analytical thinking and decision-making capabilitiesWe are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.Salary range$131,200—$196,800 USD