Analyst II – LC-MS / Peptide Analysis

NxtGen is a growing cGMP analytical testing laboratory specializing in peptide and protein characterization. We are seeking an Analyst II to support routine analytical testing with a focus on LC-MS and peptide analysis.This role is ideal for candidates with hands-on experience who can operate independently and contribute to data quality, method execution, and laboratory efficiency.Key ResponsibilitiesPerform routine and non-routine LC-MS analysis (Agilent systems preferred) for peptide identification, characterization, and impurity profiling Conduct HPLC/UPLC testing for purity, related substances, and method-based analysis Prepare samples, solvents, calibration standards, and system suitability solutions Process, review, and verify analytical data for accuracy and completeness Generate and review analytical reports in accordance with internal procedures Perform basic troubleshooting of LC-MS and chromatographic systems Support method transfer, verification, and routine method execution Assist with investigations (e.g., OOS/OOT) and deviation documentation as needed Support endotoxin (LAL) and sterility testing as required Maintain complete and compliant documentation in accordance with GDP and ALCOA+ Follow SOPs, cGMP/GLP requirements, and safety procedures Maintain a clean, organized, and audit-ready laboratory environment QualificationsBachelor or Master’s degree in Chemistry, Biochemistry, or related field 2–5 years of analytical laboratory experience Hands-on experience with LC-MS and HPLC/UPLC systems (Agilent preferred) Experience with peptide analysis strongly preferred Familiarity with data processing and chromatographic/mass spectral interpretation Strong attention to detail and documentation skills Why Join NxtGenWork in a peptide-focused analytical laboratory with advanced instrumentation Expand expertise in LC-MS, impurity profiling, and peptide characterization Be part of a growing, collaborative, and fast-paced environment Contribute to cGMP-compliant testing for commercial and research clients Working ConditionsEnvironment: Laboratory setting with exposure to chemicals, biological materials, and laboratory equipment.Schedule: Monday – Friday, 7:00 AM – 3:30 PM.Location: North Charleston, SC.PPE: Required use of personal protective equipment (lab coat, gloves, safety glasses).Equal Employment OpportunityNxtGen is a Disabled and Veteran Equal Employment Opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.Benefits Competitive salaryHealth, dental, and vision insurance401(k) with company matchPaid time off and holidaysEmployee Purchase Program