Principal Clinical Scientist

Principal Clinical Scientist (AI Training)About the RoleWhat if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and evaluates medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level clinical rigor to the AI systems that are redefining biomedical research.At Alignerr, we partner with the world's leading AI research labs to build and train cutting-edge models. In this role, you won't just consult on the margins - you'll be at the center of ensuring that AI systems reason about clinical data the way the world's most demanding regulators expect.This is a fully remote, flexible contract role designed for senior clinical professionals who want to work at the frontier of AI without leaving their scientific roots behind.Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10-40 hours/week What You'll DoDesign and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systemsInterpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standardsEvaluate AI-generated clinical analyses for scientific soundness and regulatory relevanceProvide expert, structured feedback that improves how AI models reason about clinical trial data, endpoints, and outcomesServe as a domain authority at the intersection of clinical science and frontier AI development Who You AreSenior-level clinical scientist with hands-on experience designing trial protocols for regulatory submissionDeep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodiesStrong grounding in clinical research methodology, biostatistics, or translational scienceRigorous, detail-oriented thinker who can clearly articulate why something meets - or falls short of - regulatory expectationsSelf-directed and comfortable working independently in an asynchronous, remote environment Nice to HavePrior experience with data annotation, data quality review, or AI evaluation workflowsBackground in clinical data management or medical writing for regulatory submissionsFamiliarity with AI tools or interest in how machine learning is applied in biomedical contexts Why Join UsWork directly on frontier AI systems making a real impact on clinical and biomedical researchFully remote and flexible - structure your hours around your life, not the other way aroundFreelance autonomy with the intellectual depth of genuinely meaningful, senior-level workInfluence how AI understands, evaluates, and communicates real-world clinical evidence at scaleCollaborate with world-class AI researchers and clinical domain experts across the globePotential for ongoing work and contract extension as new projects launch