Variant Curation Scientist

We’re looking for a senior leader in Variant Curation to help define how genomic data is interpreted, classified, and reported in one of our new genetic laboratories in Atlanta, GA.You’ll work closely with laboratory leadership, bioinformatics, clinicians, and genetic counselors to ensure genomic results are accurate, defensible, and meaningful in real clinical settings. If you’re motivated by building something from the ground up and setting a high bar for quality in clinical genomics, this is a unique opportunity to lead that work.Why this role mattersGenomic testing only delivers value when results are trusted, understood, and actionable. This role exists to ensure that every variant interpretation meets the highest standards of clinical quality, scientific integrity, and regulatory compliance—while building frameworks that scale as testing volume and complexity grow.What you’ll ownVariant interpretation & clinical frameworksLead the development and oversight of variant interpretation frameworks across germline and somatic assays. Ensure alignment with established clinical guidelines and evolving scientific evidence.Curation workflows & scalabilityDesign and implement scalable processes for variant curation, classification, and reclassification. Build standardized workflows that support high-throughput, high-complexity genomic testing.Clinical reporting & translationEnsure genomic findings are translated into clear, clinically actionable reports for physicians and care teams. Maintain a high standard for clarity, accuracy, and clinical relevance.Quality, compliance & consistencyEstablish SOPs and quality frameworks that support consistency, defensibility, and traceability of variant classifications. Maintain rigorous review processes across all stages of interpretation.Cross-functional collaborationPartner with laboratory leadership, bioinformatics, and assay development teams to refine interpretation pipelines and reporting infrastructure. Work closely with clinicians, genetic counselors, and scientists to support accurate and timely results.Test development & innovationSupport the development, validation, and clinical implementation of new genomic assays. Contribute to continuous improvement in interpretation workflows and data utilization.Data stewardship & knowledge sharingContribute curated variant data to public knowledgebases such as ClinVar and support the development of internal knowledge systems. Help strengthen how genomic data is captured, organized, and used across the organization.Scientific contribution & impactParticipate in translational research and clinical collaborations that expand the impact of genomic testing and advance precision medicine.What success looks likeA robust and scalable variant interpretation framework that supports Phytest’s expanding genomics portfolio. Consistent, high-quality clinical reports that translate genomic complexity into actionable insight. Strong integration of variant science into laboratory operations, enabling efficient test development and delivery. Effective collaboration across clinical, scientific, and operational teams.You may be a great fit if you have·      A PhD in genetics, molecular biology, or a related field, or a Master’s degree with strong relevant experience. ·      At least 2 years of experience in clinical genomics or a related field, including postdoctoral work. ·      A strong understanding of ACMG variant curation guidelines and the relationship between genomic variation and human disease. ·      Expertise in genetics, genomics, molecular biology, or clinical medicine concepts.·      Experience with data quality assessment and the ability to communicate complex genetic information clearly. ·      Strong written and verbal communication skills, particularly in medical and scientific contexts. ·      Proficiency with Microsoft Office tools including Excel, Word, PowerPoint, and Outlook. ·      MB(ASCP) certification is preferred. Experience with bioinformatics analysis is a plus.What Phytest offersCompetitive compensation along with medical, dental, and vision insurance, paid time off, paid holidays, and a 401(k) with a 100% company match.