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We strive to dissect the molecular, cellular, and tissue-level mechanisms by which genetic variants modulate disease risk, with a major focus on the role of microglial cell function in vitro and in vivo.
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Experience in immunoassays (ELISA, MSD, Western Blot, etc) and molecular biology techniques (mRNA isolation, qPCR) Perform basic molecular biology assays including mRNA isolation, Taqman qPCR, NanoString.
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The successful applicant will execute a broad research program focused on growing stem cell technology in the Vedantham Lab and will include probing specific developmental pathways in vitro using the hiPSC differentiation system, CRISPR screening of hiPSC-derived cardiomyocytes, application of standard molecular biology techniques and next generation sequencing (scRNseq, scATAC-seq, ChIP-Seq), and may eventually involve tissue engineering.
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Brain dissection, cyrosectioning, and immunohistochemical stainingRodent handling and dosing including oral, intraperitoneal, and subcutaneousTissue dissection and blood collectionCellular and molecular biology experimentsIn vitro experiments (primary cell culture)Data and statistical analysesScientific oral and poster presentationsMaintain good laboratory practices (GLP) and lab notebook Qualifications Researcher I- BA/BS degree in an appropriate biological field.
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Experience in assay development, mammalian cell culture, ELISA, Western blotting, qPCR, and experience in standard molecular biology techniques such as cloning, protein expression and purification is preferred.
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Specifically, the Research Technician will be responsible in performing the following tasks: 1) cell culture, 2) testing in vivo treatment efficacy in mouse nerve and ovarian cancer models, and performing treatment and tumor measurements, 3) molecular biology analysis to study mechanisms, 4) process patient samples for translational studies.
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Wet lab molecular biology and biochemistry experiments such as gene expression/qPCR, protein analyses by Western Blot, blood cell/splenocyte isolation, FACS, immunoassays, Able to work in in vitro and in vivo environments, especially with animal handling.
$26.76 - $38.8 an hourFull-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Required Job Qualifications A degree in Biology, Biomedical Sciences, Chemistry, Biochemistry, Molecular Biology, Neuroscience or related field. Research Associate I, II, or III positions available in biomedical sciences laboratories studying the role of selected molecules on biological processes in vivo or in vitro.
$50,000 - $75,000Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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The ideal candidate will have experience of experience of molecular biology, cell biology and in vivo assays. Our startup biotech client with incredible technology and deep pockets has tasked Scientific Search in finding them a Research Associate in their in vitro biology group.
$85,000 - $105,000 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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What you’ll do: We seek highly self-motivated and creative post-doctoral researchers, particularly those who recently acquired Ph. D. or M.D. Candidates should have in-depth knowledge of molecular biology, biochemistry, high-resolution imaging, and electrophysiology.
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This position additionally requires providing technical support for in vitro and in vivo experiments, encompassing molecular biology, cell culture, and flow cytometry, for the benefit of post-doctoral fellows and graduate students within the laboratory.
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Experience with molecular biology and functional genomics techniques such as CRISPR and siRNA. The Associate Scientist III/Scientist I, Neuroscience will partner with scientific and project teammates to develop and execute mid/high throughput biochemical/cellular assays, in vitro mechanistic experimentation, and explore novel models to advance early targets through our pipeline.
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The potential candidate is expected to perform various cell and molecular biology techniques, PBMC and exosome isolation from human serum, bioinformatics, in vitro and in vivo experiments to evaluate the combination drug therapy in glioblastoma and the development of biomarkers for pseudoprogression.
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Bachelor’s Degree in Biology, Biochemistry, Chemistry, Molecular Biology, Biomedical Science of Genomics. Stays current with industry trends and market intelligence, specifically with respect to genetic literacy enzymes/applications, to understand key competitive issues in relation to process, pricing and business strategy in the NGS, molecular diagnostic, and nucleic acid synthesis market segments.
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Bachelor's degree in Molecular Biology, Microbiology, Biochemistry, or similar degree required. Previous course work in immunology, microbiology cell biology, biochemistry, virology and chemistry is desirable.
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