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We are seeking to hire an Associate Scientist with molecular biology experience to join the RNA Therapeutic Discovery Team. The successful candidate will work both independently and as part of a team to test novel RNA therapeutics.
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Design and execute experiments using cellular, biochemical, and molecular biology techniques, including DNA and RNA extraction, PCR, real time PCR, droplet digital PCR, and other techniques.
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Carry out molecular biological experiments, including cell culture, tissue homogenization, protein and RNA extraction techniques, multiplex enzyme-linker immunosorbent assay, Western blotting, RT-PCR, tissue handling and flow cytometry.
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Experience with current molecular biology techniques including in vitro transcription and translation, DNA/RNA extraction, PCR, and NGS. Collaborate closely with computational biology, gene editing and preclinical teams.
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Develop other molecular biology-based assays using techniques such as cloning, DNA/RNA/protein extraction and RT-PCR. Experienced in cellular viability assays, and molecular biology techniques, such as cloning and qPCR.
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Experience with standard cell and molecular biological assays such as ELISA/Luminex, nucleic acid extraction, qPCR, immunofluorescence staining and confocal microscopy, cell proliferation/viability assays, cytotoxicity assays, flow cytometry / FACS, magnetic cell sorting.
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The successful candidate should have experience in at least one of these areas: molecular biology (RNA extraction, qPCR), electrophysiology (Patch-clap, EPSP recording), and fluorescence imaging (confocal, two-photon.
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Molecular biology techniques (cloning, PCR, DNA extraction, gel electrophoresis) Our work is highly interdisciplinary and touches on aspects from many fields including bioengineering, protein engineering, biochemistry, synthetic biology, molecular biology, microbiology, structural biology, genetics, bioinformatics, and quantitative biology.
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Domain knowledge evidenced by a graduate degree and applied experience in genetics, molecular biology, bioinformatics, or related field. Knowledge of information extraction (IE), data integration, ontology, semantic technology, machine learning (ML), or natural language processing (NLP.
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The ideal candidate for this position will have hands-on laboratory research experience and a working knowledge of molecular biology techniques (e.g. PCR, DNA extraction, sequencing.
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Ph. D. and 1-3 years of work experience or Master degree with equivalent level of experience, in Biochemistry, Molecular Biology, Immunology, Chemistry, Bioengineering or related discipline.
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The ideal candidate will possess a deep understanding of tissue culture, cell line maintenance, cell-based assays, and proficiency in molecular approaches such as DNA/RNA extraction and PCR techniques.
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Work with all types of Molecular Biology techniques including: DNA and RNA extraction, Polymerase Chain Reaction (PCR), Reverse Transcriptase PCR, Southern Blotting, agarose gel electrophoresis, restriction digest, Capillary Electrophoresis, Sanger Sequencing, Probe Hybridization, Bead Capture technology, Microarray technology and more.
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Experience with current molecular biology methods (e.g., DNA extraction, PCR, DNA design software). This is a highly dynamic and collaborative institute, working to apply disease agnostic technology such as proteomics and functional genomics, as well as biochemistry, computational biology, bioinformatics, and drug development to unravel the molecular networks underpinning host-pathogen interactions and developing targeted therapeutics.
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Competent in performing molecular techniques- nucleic acid extraction (both manual and automated), various PCR techniques including RT-PCR set-up, standardization, and validation procedures.
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