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Broad understanding of oncology disease area; experience in immuno-oncology highly desirable. The ideal candidate is an MD or MD/PhD scientist with a clinical perspective, coupled with a track record of exceptional achievement in oncology therapy development.
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Extensive knowledge and understanding of other areas of cancer cell biology including but not limited to DNA damage and repair, immuno-oncology, oncogenic signaling, ADC biology and/or apoptosis.
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You will also maintain technical expertise in preclinical safety approaches applied to Immuno-Oncology therapeutics or Antibody Drug Candidates and awareness of industry trends. We are seeking a highly motivated Senior Scientist who will contribute to the discovery of novel oncology medicines that include T Cell Engagers and Antibody Drug Conjugates for haem and solid tumor indications.
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They are an upcoming Immuno Oncology biotech company with two products in the pipeline and one poduct in pre-clinical. Stay informed about the latest advancements in medicinal chemistry, drug discovery technologies, and therapeutic areas of interest.
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As part of the Global Oncology Products and Pipeline Strategy team, you will report to Vice President, Global Oncology Products & Pipeline Strategy and work with Global Business Development (GBD), Center for External Innovation (CEI), New Products Planning (NPP), Oncology Therapeutic Area Unit (OTAU), and Oncology Drug Discovery Unit (ODDU) to evolve and drive Takeda Oncology BD goals and strategy.
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The successful candidate will engage in innovative immune-oncology research, and contribute to every stage of pre-clinical drug discovery and development. We are seeking an experienced Scientist to join the Immuno-Oncology group to support our efforts on developing strategies to overcome immune-checkpoint inhibitor therapy resistance in liver cancers including primary hepatocelluar carcinoma (HCC) and tumors from other organs metastasized to livers.
$45Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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The successful candidate will have the ability to bring creative/innovative clinical designs to define and apply the most effective approach across Marengo's R&D pipeline while working closely with drug development teams (e.g., drug discovery, immunology, clinical development, clinical operations, regulatory, safety, and pharmacovigilance.
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Drug discovery experience in immunology/ immuno-oncology is strongly desired. PhD in pharmacology, immunology, immuno-oncology, biology or related discipline, post-doctoral experience, and 3-5 years of biotech/ pharma experience.
$125,000 - $145,000 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy, and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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We are a team of innovators dedicated to empowering researchers in immunology, immuno-oncology, and neuroscience to push the boundaries of scientific discovery and drug development.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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Significant clinical research experience (in industry, academic or CRO environment) related to drug development, design and/or conduct of clinical studies in oncology and/or malignant hematology is required.
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As a Computational Biology Partner for Cancer Immunology, your contributions will directly impact foundational elements of drug discovery, including target identification, target validation, disease selection/expansion, and translational biomarkers.
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The Oncology Drug Metabolism and Pharmacokinetics (DMPK) department provides ADME/PK, as well as translational PK/PD Modeling & Simulation to support our discovery and development portfolio.
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Industry or Academic experience in drug development required with experience in malignant haematology clinical trials strongly preferred. Drug Development/Clinical Development Planning: Demonstrates a consistent track record to both independently complete, and lead peers in completion in components of sophisticated plans, related documents, appropriate methodologies, measures, analytical plans and evaluation tools.
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