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In our state-of-the-art histology and immunohistochemistry laboratory, you'll support a variety of programs, ranging from discovery to clinical trials, all aimed at advancing antibody therapeutics.
$170,625 - $284,375 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Work with medicinal chemistry and pharmacology teams as part of drug discovery efforts to validate targets and optimize novel small molecule therapeutics. Leverage state-of-the-art immuno-oncology approaches to develop insights into new IO-related targets and impacts on novel therapeutics on the immune system.
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Strong knowledge of biomarker discovery and development in clinical trials, including assay development, validation, and data analysis. BeiGene is currently developing innovative therapies in oncology, immunotherapy, and inflammation with different modalities including traditional small molecules, protein degraders, monoclonal antibodies, ADCs, bispecific antibodies, cell therapy, mRNA et al. Key Responsibilities: Develop and implement global clinical biomarker strategies for our oncology and immuno-therapy programs.
$199,800 - $269,800 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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Precigen (Nasdaq: PGEN) is a dedicated discovery and clinical stage biopharmaceutical company advancing the next generation of gene and cell therapies using precision technology to target the most urgent and intractable diseases in immuno-oncology, autoimmune disorders, and infectious diseases.
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Xilio Therapeutics is a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments.
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Collaborate with internal Regeneron laboratories (e.g. Discovery Research, Molecular Profiling, Regeneron Genetics Center, DNA core, BioAnalysis, etc.) Collaborate with Discovery Research and product development to facilitate appropriate incorporation of clinical biomarker strategies for molecules in discovery phases (leading to candidate molecule selection.
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The group supports early safety assessment of T Cell Engagers, Immuno-Oncology Therapeutics, Cell Therapies and Antibody Drug Conjugates. - A proven understanding of drug discovery and development, with a strong scientific track record with experience of independent research in industry, biotech, or academic setting, working with relevant T Cell Engagers or Antibody Drug Conjugates.
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At least 10 years experience in Business Development and Licensing within pharmaceutical or biotech sector, with focus on oncology, hematology or immuno-oncology. As part of the Global Oncology Products and Pipeline Strategy team, you will report to Vice President, Global Oncology Products & Pipeline Strategy and work with Global Business Development (GBD), Center for External Innovation (CEI), New Products Planning (NPP), Oncology Therapeutic Area Unit (OTAU), and Oncology Drug Discovery Unit (ODDU) to evolve and drive Takeda Oncology BD goals and strategy.
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Comprehensive understanding of DMPK and pharmacology/safety aspects of drug discovery and development. As an Associate Director in Translational PKPD, you will drive strategy and provide global leadership in DMPK science on small molecules, Antibody Drug Conjugates (ADCs) and Radio Immuno Conjugates (RICs.
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Indivumed Services, a Crown Bioscience Company, is a global contract research organization (CRO) that offers an industry-leading oncology biobank and a range of service platforms to advance oncology and immuno-oncology drug discovery and development.
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The postdoctoral fellow will work closely with the OED safety team as well as other cross functional members of the oncology early development team (e.g. preclinical safety and toxicology, discovery, pharmacology and pharmacokinetics, regulatory, statistics) bridging preclinical/discovery expertise to the very early phases of clinical safety (e.g. pre-IND interactions, and IND submission and initial FIH phase.
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Knowledge of preclinical and clinical development is a prerequisite, as is knowledge of Immuno-Oncology and emerging therapies in Oncology. Liaison between the clinical safety team and discovery leads on newly explored target/platforms in oncology.
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In addition to our ongoing programs in antivirals and prodrug platform technologies, our current efforts include designing and developing novel non-opioid analgesics, anti-anxiolytics, NMDA receptor modulators, chemotherapeutics and immuno-oncology agents.
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Co-represent Takeda Oncology at major oncology related meetings such as: AACR, ASCO, ESMO, ASH among others. In collaboration with Global (and Local) Business Development (GBD), Center for External Innovation (CEI) and New Products Planning (NPP), identify, monitor and review near-term (within 3 years of regulatory approval) oncology partnering opportunities that meet the Takeda Oncology BD strategy.
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