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1-5 years experience in viral vector/cell therapy (or biopharmaceutical) based GMP manufacturing operations including direct experience in cell culture, cell selection, recovery, purification, and/or aseptic fill/finish.
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Research Associate, Viral Vector and Gene Delivery Process & Analytical Development. If you want to challenge yourself, accelerate your career, and give new hope to patients, theres no better place than here with our Cell Therapy team.
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We are seeking an enthusiastic, self-driven individual to join the Gene Delivery Process & Analytical Development team as a Research Associate. Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today.
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GenScript ProBio is the subsidiary of GenScript Biotech Corporation, proactively providing end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers.
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The candidate’s main responsibilities will include: a) novel assay development, b) in-vitro T cell circuit design and validation, c) establishment of in-vivo tumor models, d) compiling pre-clinical results to support the designation of clinical vector design, and e) leading the in-vitro and in-vivo pharmacology characterization of therapeutic product candidates in collaboration with a process development team towards an IND filling.
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Akouos, a wholly owned subsidiary of Eli Lilly and Company, is building a leading gene therapy company focused on hearing disorders. Akouos is developing targeted adeno-associated viral (AAV) vector-based gene therapies for sensorineural hearing loss, the most common form of hearing loss and one of the most common of all sensory disorders, in conjunction with a delivery device / delivery system to administer these gene therapies to the intracochlear space.
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The individual will focus and work along a group of scientists to develop small- and large-scale lentiviral vector (LVV) gene therapy vectors across various preclinical programs and disease areas.
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Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein.
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Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas.
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Description About the role: The Laboratory Technician, Pre-Clinical Vector Manufacturing reporting to the Vector Manufacturing Team Lead is responsible for supporting routine laboratory operations related to manufacturing research-grade recombinant Adeno-associated virus (rAAV) vectors as part of Client's Vector Core. The rAAV vectors manufactured support capsid technology development, intellectual property portfolio and progression of internal and external early-stage gene therapy programs.
$26 an hourExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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In this role, the Molecular Biology Quality Control Analyst I will be responsible for supporting the gene therapy program pipeline, including but not limited to routine GMP testing of AAV vector analytical methods such as GC titer determination by ddPCR and qPCR, impurity testing, and other methods as needed.
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GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
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BS or MS in Molecular Biology, Cell Biology, Biochemistry or a related discipline with 1+ years industry experience. Experience with viral vectors is not required but experience with biologics. Ensure laboratory inspection readiness and assists with troubleshooting/continuous improvement as needed.
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We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products.
$128,000 - $149,000 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.
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