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Conduct formulation and/or process screening to improve biophysical characteristics and in vivo gene editing in animal models. The Scientist will work on developing safe and potent delivery systems to enable in vivo gene editing.
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MS or PhD in Computer Science, Bioinformatics, Computational Biology, or a closely related field. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response.
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Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein.
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Scientist - PhD - Biologist. Apply molecular and cell-based assays including but not limited to RNA transfection, RNA & protein isolation, gene expression analysis (RT-qPCR & RNA Sequencing), western blot, and fluorescence immunocytochemistry.
$100,000 - $120,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Plan and execute in vitro safety screens to lead optimize small molecules, ASOs and gene therapy vectors. PhD in Toxicology, Pharmacology or related sciences (or DVM) and a minimum of 10-15+ years of industry experience in Toxicology.
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Preferably experience with animal models of disease, gene expression analysis, cell culture, gene transfection, viral gene transfer, tissue level analysis (histology, IHC). Click here to learn more about our Postdoctoral Program and Services: REQUIREMENTS: PhD in Biology, Cell Biology, Molecular Biology or related field with 0-2 years of relevant experience.
$64,480 - $66,600 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Experience in ELISA assay development, cell culture, gene expression with RT-PCR and/or enzyme kinetics is desirable. Educational/Training Requirement: For Research Associate: BS/MS in biology, biochemistry and other related fields For Scientist: PhD in biology, biochemistry and other related Basic understanding and training in Biology, Biochemistry and any related field.
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Reporting to the Associate Director of Analytical Development, the Scientist will be responsible for the development of biophysical and analytical chemistry methods to further gene therapy products throughout clinical development, as well as performing BLenabling characterization studies.
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We encourage applicants with strong expertise in cell and gene therapy, particularly those with a PharmD or PhD, to apply. We share a passion for seeking gene therapy cures for devastating diseases and making a difference for patients.
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Candidates must hold a PhD, MD or both, and be board certified/eligible in Clinical Molecular Genetics, Laboratory Genetics and Genomics, or Molecular Genetic Pathology by the American Board of Medical Genetics and Genomics (ABMGG) or the American Board of Pathology (ABP.
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Bachelor's, Master's or PhD degree in Biology, Chemistry, Pharmacy, Regulatory Affairs for Drugs, Biologics or Medical Devices, or another life-science field. The Director/Vice President Regulatory affairs for iPSC derived cell therapies will manage the execution of global regulatory strategies for investigational and marketed cell and gene therapy products.
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Terminal degree (DVM, PhD, MD) in pharmaceutical, biological, or chemical sciences. We aim to begin generating IND- and IDE-enabling data for novel cell, gene, and oncolytic therapies that oftentimes require co-labeling with drug delivery devices.
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Candidates should hold a PhD in Animal Science, Neuroscience, or related field with emphasis in biomedical swine research related to neurological disease or injury, neurodevelopment, neuroimaging, cognition and behavior, and other closely related biomedical areas of interest.
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Voyager's TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors.
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We use diverse approaches in genomics, bioinformatics, systems biology and immunology to understand how epigenetic regulation of gene expression programs are disrupted by genetics and environment.
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