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Perform molecular biology procedures (i.e. DNA/RNA/protein isolation and characterization, RT-PCR, enzyme assays, and multi-well plate assays) and flow cytometry-based micronucleus assays.
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Ph. D. or equivalent in virology, molecular biology, antiviral therapeutics or drug discovery, or a related discipline; at least 8-12 years post-PhD work experience in an academic or biopharma/biotech setting.
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Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, and pharmacology. Experience working with flow cytometry and standard molecular biology techniques.
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Background in oncology, cancer biology, cancer drug discovery and ADCs. Experience with tissue culture and diverse molecular biology techniques. Apply cellular and molecular biology laboratory techniques to preclinical research projects in the area of cancer biology.
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We are seeking a highly motivated and skilled candidate to join Novartis Biomedical Research as a Discovery Postdoctoral Fellow within the Discovery Sciences (DSc) department to work on expanding the scope of covalent drug discovery.
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Provide scientific and strategic direction, oversight, and guidance to staff for large and small molecule bioanalysis, cell and molecular biology, immunology and biomarkers, analytical chemistry, molecular imaging, clinical pathology lab operations, sample management and archives.
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Project Scientist - UCLA G.O. Discovery Laboratory University of California Los Angeles Requisition Number: JPF09292 The G.O. Discovery Laboratory within the UCLA Eli and Edythe Broad Cell Research Center, which is closely affiliated with the Jonsson Comprehensive Cancer Center and the Molecular Biology Institute, invites applications for a Project Scientist at the Assistant, Associate or Full Project Scientist level.
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Strong background in oncology, cell biology, immunology, and small molecule drug discovery Doctorate degree in immunology, molecular biology or related discipline with experience in haematology-oncology.
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PhD, MD or MD/PhD degree in a relevant scientific field (e.g., cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years experience in drug discovery or drug development.
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They are used in drug discovery, toxicity testing, stem cell banking, and cell therapy development. Demonstrated capability with cell culture, flow cytometry, and/or molecular biology methods.
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Our group is responsible for expanding our understanding of RNA biology, leveraging proximity biology to tackle the "undruggable genome", and advancing Amgen's drug discovery pipeline.
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Demonstrated record of high-proficiency, hands-on molecular biology experience with PCR-based assays and technical knowledge of high-throughput genomic profiling technologies with emphasis on Illumina sequencing platforms and complex library preparation workflows for bulkRNseq, 10X Genomics scRNseq, and 10X Genomics Visium spatial transcriptomics.
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At least 2 years’ laboratory experience working in NGS, with a focus on liquid handling and automation being preferable (HTS, Assay Development, or molecular or structural biology backgrounds will also be considered) Good understanding of genomics, drug discovery, and structural biology.
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Apply knowledge of molecular biology, genetic engineering, and chemistry to peptide discovery and optimization activities for a given biological target of interest. Drug Hunting Focus: The candidate is expected to exhibit strong problem-solving abilities and be familiar with understanding and resolving issues that lie at the interface of peptide discovery, peptide engineering, pharmaceutical developability and formulation, and biology.
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At 1910 Genetics, we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, genetics, data science, and software engineering to develop drugs for previously undruggable targets.
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