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Prior experience with mRNA upstream and downstream process development. At least 2 years of experience working in an industry lab with a proven record of developing and executing novel mRNA upstream and downstream process.
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As a subject matter expert, you will provide valuable insight and direction when interfacing with internal and external stakeholders on chromatography experiential design, process, bridging, optimization, scale-up, downstream analysis, and troubleshooting.
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Help determine process parameters range for cell culture and downstream processing to optimize PSC starting material yield and quality in a bioreactor system. Ph. D or MSc. degree in a Biological Science, such as Biochemistry, Immunology, Molecular Biology, or similar.
$120,000 - $125,000Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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The Senior Scientist I will play a key role in the developing downstream purification process development for various modalities such as mAbs, ADCs, bio-specifics, gene therapy, etc. Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bio-specifics and antibody drug conjugates (ADC.
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They will be responsible for following Current Good Manufacturing Practices (cGMPs) and carrying out a variety of functions related to Upstream (cell culture) and Downstream (purification) biopharmaceutical manufacturing.
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Under the general scientific and administrative direction of Principal Scientist in Downstream and working in conjunction with internal and external partners, this individual will support these late stage and commercial biologics program activities within BPDC. The individual will develop and demonstrate scientific, experimental and tech transfer skills focusing on downstream processing.
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Cross-train on and provide support for upstream and downstream process development operations. This position requires a Bachelor's and/or Master's degree in either Cellular and Molecular Biology, Biochemical Engineering, Biochemistry, Virology, or related field with 0-3+ years of experience.
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Minimum of B.S. in biology, bioengineering, biochemistry, or equivalent and 3-5 years of relevant experience in the biotech or pharmaceutical industry. Implement and lead technology transfer, process validation, and GMP manufacturing in support of Drug Product fill/finish for early and late-stage clinical supply through launch/BLA.
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Lead an integrated process development, analytical development, and manufacturing team across upstream and downstream functions for mRNA production. Ph. D. in Chemical/Biomedical Engineering, Biochemistry, or a related discipline with 8+ years of relevant industrial experience, M.S. with 10+ years, or B.S with 12+ years.
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10+ years Downstream Process Development experience related to biochemical engineering and/or protein biochemistry, scale-up principles, and manufacturing of Biopharmaceuticals (cGMP.
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The Director, Manufacturing Operations will oversee, lead Upstream & Downstream operations; manage process/cleaning validation, scale up & technology transfer; direct personnel for efficient use of equipment in accordance with the production plan; as well as be responsible for the costing & budgeting for the products manufactured by Kashiv Biosciences LLC.
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As a Process Development Scientist II, you will help our clients to deliver lifesaving and life changing therapies to patients in need. Bachelor’s Degree in biology, chemistry, biochemistry, (bio)chemical engineering, biomedical engineering, or a related field.
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Support tech transfer of new products and processes to ensure smooth transition from process development/clients into GMP manufacturing. Minimum B.S. degree in biochemistry, chemical engineering, bioengineering, or related technical field.
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3 + years of experience in Process Engineering related to biochemical engineering and/or protein biochemistry, scale-up principles and manufacturing of biologics (cGMP) Upstream and/or Downstream process knowledge and hands on cell culture and/or purification pilot/clinical/commercial experience with regard to the manufacture of a biological drug substance.
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Hands-on protein purification and downstream process development at scales from 0.1-50 L. Strong understanding of protein biochemistry as it applies to purification and enzyme characterization.
ExpandApply NowActive JobUpdated 4 days ago
downstream biochemistry process jobs
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