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These projects include NIH-funded studies using FUS to enhance the delivery of medications (e.g., nanoparticles encapsulated with antiretroviral medications and CRISPR agents to treat HIV) and MR-guided FUS to modulate brain function to treat animal models of addiction.
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We are seeking a highly motivated individual to join our R&D team to develop novel therapeutics using CRISPR and gene therapies. Areas of in vivo development focus include CNS, ophthalmology, neuromuscular, and pulmonary, among others.
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Preferred Qualifications Experience with cellular and molecular biology, CRISPR gene editing and/or drug discovery. Current projects include CRISPR genome editing of human stem cells, and high content and high-throughput drug screening approaches to identify small molecules relevant to RGC regeneration and OL development, with the ultimate goal of developing novel therapeutic strategies for patients with blinding retinal diseases and demyelinating neuropathies.
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Perform routine laboratory research activities such as: molecular biology and genetic procedures such as gene cloning, gene modifications, including CRISPR mediated gene modification, PCR, restriction enzyme digestions, gel electrophoresis, blotting, and DNA extractions.
$44,500 - $48,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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To accelerate and expand its efforts,CRISPR Therapeuticshas established strategic partnerships with leading companies includingBayerand Vertex Pharmaceuticals. CRISPR Therapeutics is seeking a highly passionate, creative, and motivated mRNA scientist to join our In Vivo Technical Operations department in Boston, Massachusetts.
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Founded in late 2015, KSQ is a clinical-stage biotech that has rapidly advanced the field of CRISPR-enabled functional genomics, from in vitro cell autonomous screens to more complex genome-scale screens of immune cells in vivo.
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The Inside Sales Representative proactively promotes the sale of IDT's full portfolio of products, including custom oligonucleotide solutions across key application areas such as qPCR, CRISPR, Functional Genomics, Synthetic Biology, and Next Generation Sequencing.
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Bachelor's degree in a Life Science field with equivalent experience in Biology, Genetics, Biochemistry, Molecular Biology or related field required. Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications.
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Applying molecular and cell biology approaches to cell lines and animal studies, including immunostaining, microscopy, flow cytometry, epigenetic assays, Crispr/Cas strategies, among others. The successful candidate must have previous experience and be proficient in mouse husbandry, PCR-based genotyping, cell culture, flow cytometry, as well as DNA, RNA, and protein isolation and detection techniques.
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Stay up to date with latest CRISPR and protein engineering literature, conduct regular literature reviews in collaboration with Dr. Kellogg and other Kellogg lab members. Collaborate with other Kellogg lab members to design & clone large DNA libraries using state of the art machine learning methodsMap phylogenetic relationships of CRISPR-associated systems to map functional interactions.
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Caribou Biosciences is a leading clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. Technical expertise in Multi-Color Flow Cytometry and ability to perform minor troubleshooting.
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Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA. Some training may be provided · Hands on experience in working with CRISPR, siRNA and shRNA is a plus.
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Determination of on- and off-target CRISPR-based editing by next generation sequencing. Determination of on- and off-target CRISPR-based editing by next generation sequencing. We are seeking a Scientist to be part of a team focused on next generation sequencing in genome and cellular engineering in the Genomic Medicine Unit.
$50.4 - $57.4 an hourExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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It is our mission to deliver innovative genomics product leveraging our leadership in DNA Synthesis and dedication to the customer experience. Molecular Biology or similar lab experience. This position is eligible for a remote work arrangement in which you can work remotely from your home.
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Experience and knowledge in gene and cell therapy, mRNA/LNP, CRISPR/Cas technology preferred. Hands-on expertise in tissue culture and cell-based assays (including general tissue culture, cell banking, cell proliferation, electroporation, transfection, transduction, flow cytometry, AAV, and ELISA.
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