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Candidate must have strong technical skills in mammalian cell culture, and cell-based assay development using cell lines and primary cells. We help clients with new skilling, talent strategy, leadership development, employee experience, transformational change management and beyond.
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The successful candidate will have a strong experimental background with an established track record of hands on in vitro/in vivo ADME assay support and technical problem solving. Strong understanding of drug metabolism and ADME principles including enzyme kinetics, analytical method development, metabolite profiling and structural elucidation.
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4+ years of hands-on experience in marketing, sales, and/or molecular assay development with increasing scope and responsibility in the genomics and molecular diagnostic arenas preferred.
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Specific technical background in assay development (cellular or biochemical) and experience with various assay readouts. The successful candidate will be an integral member of the DST research team and work closely with various Research functions such as medicinal chemistry, structural biology and protein therapeutics to advance transformational therapies into clinical development for patients.
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Established capability to design, conduct, optimize and execute on novel biochemical and cell-based assay development efforts in the lab supporting HTS and project deliverables. Cell culture, media development, and cell-based assay development.
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Experience with cell culture (cardiomyocytes is preferred) and cell-based assay development. Experience with cell culture (cardiomyocytes is preferred) and cell-based assay development. Understanding of drug discovery process is preferred.
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It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations.
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As a Scientist in assay development you will develop, optimize, and execute novel enzymatic and cell-based assays in high-throughput screens using conventional approaches and robotics. As part of your day-to-day you will learn, apply, and incorporate automation solutions during assay development, execution, troubleshooting, data analysis, and reporting while investigating and identifying new methods and technologies to generate reliable and reproducible data.
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Utilizes scientific awareness to bring innovative ideas for assay and method development. Responsible for execution of assay/method development experiments. Responsible for performing complex assay/method development.
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Establishes and executes development project plans (e.g., process and assay development, assay qualification, support tech transfer of processes) from cGMP manufacturing and assays to quality control.
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This is an exciting research opportunity to explore the genetic potential and phenotypic diversity of fruit quality traits in the development of superior Driscoll's berry varieties. 6+ years’ experience in Analytical Chemistry and 2+ years’ experience in Research and Development including sample management, data management and project management.
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Experience with assay development, Biomarker Analysis (dPCR, qPCR, Flow, Luminex, ELISA), DNA/RNA/protein analysis, cell-based potency assays, genomics/proteomics, and Next Generation Sequencing.
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Core platform technologies include Immunoassay (ELISA), Lateral Flow (Dipstick, Strip Test), Enzymatic (Acetylcholinesterase), Latex Agglutination Tests (LAT), Receptor Binding Assay (Nicotinic-acetylcholine receptor), Protein Phosphatase Inhibition Assay (PPIA), and Magnetic Particles for DNA/RNA isolation.
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In this individual contributor, lab-based role the Associate Scientist will work in a collaborative environment to perform characterization testing to support process and platform development programs.
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Establish strong cross-functional relationships to enable superior performance against scientific and company objectives, including team members across computational biology,assay development, business development, and operations.
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