AbbVie, Inc

We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio.. The Senior Scientist I will support the formulation development of protein biologics from early development through commercialization, with a specific focus on neurotoxins for therapeutics and aesthetic use.. A strong technical background encompassing protein chemistry, analytical development, and formulation development is required. g HPLC, spectroscopy, HIAC, MFI, DLS, ELISA, Karl Fisher). Prior experience in development of protein product formulations and lyophilization expertise is highly desirable

product development

Company DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.Job DescriptionThe Senior Scientist I will support the formulation development of protein biologics from early development through commercialization, with a specific focus on neurotoxins for therapeutics and aesthetic use. The successful candidate will perform laboratory work while also developing productive collaborations and communications with multidisciplinary project teams and be motivated to innovate and succeed in a dynamic, collaborative environment.Responsibilities* Develop preclinical and clinical formulations, including liquid and lyophilized dosage forms, and related drug product manufacturing processes* Transfer drug product manufacturing process to internal and external fill-finish facilities and provide on-site support as needed* Support development stability and clinical in-use studies to guide dose solution administration* Generate high-quality data based on sound scientific principles and prepare formulation data summaries, technical reports, scientific presentations, and regulatory documents* May participate in drug product development teams and contribute to the planning and execution of product development studies including formulation and drug product process development, based on project goals and timelines* Actively interact with CMC members and other AbbVie stakeholders to enable the successful development of AbbVie drug products* Drive innovation by investigating and developing novel experimental approaches and/or technologies in the field of drug product development, and raise visibility within the scientific community through external presentations and publicationsQualifications* Ph.D in pharmaceutical sciences, chemical engineering, analytical sciences, biochemistry or equivalent field with 0-3 years of experience or BS/MS degree with 8-10 years of relevant experience in the biotechnology or pharmaceutical industry* A strong technical background encompassing protein chemistry, analytical development, and formulation development is required* Candidates must have hands-on expertise in analytical techniques used for protein characterization and stability testing (e.g HPLC, spectroscopy, HIAC, MFI, DLS, ELISA, Karl Fisher)* Prior experience in development of protein product formulations and lyophilization expertise is highly desirable* Prior experience with aseptic processing and drug product manufacture processes transfer is preferred* Demonstrated experience in driving innovation is a strong plus* Excellent communication and written skills requiredAdditional InformationApplicable only to applicants

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