Orion Engineering Services

Take routine analytical measurements for cell growth, gas-content analysis, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of monoclonal antibody titers. Collaborate across CMC functions to optimize bioprocess parameters for the production of difficult-to-manufacture biologics. Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 50Ibs.. Prior experience in bioreactor operation and cell culture media preparation is a must. Industry experience in sterile fermentation techniques preferably mammalian cell culture

cell culture

Job description Scientist I 6+ month initial contract Onsite in South San Francisco, CA - 1000 Gateway Blvd. South San Francisco, CA 94080 Hourly Pay Rate: $40-43/hr (Medical benefits available at a cost) Work Schedule: Monday to Friday with infrequent weekend work maybe 3 or 4 times during assignment when fully trained. Will be able to take a weekday off when this happens Orion Group is hiring a Scientist to work with our global pharmaceutical client in South San Francisco, CA. This is an exciting chance to work with a world-class company and industry leader as well as being a part of a team pioneering the discovery of new pharmaceuticals to help save lives! If this is your career plan, then read on! Job Responsibilities: * Perform routine tasks such as media/buffer preparation, thawing of cryopreserved cells, cell culture passaging, aseptic sampling and banking competently and independently to support ongoing projects in cell culture lab * Take routine analytical measurements for cell growth, gas-content analysis, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of monoclonal antibody titers * Utilize technical expertise and available information to troubleshoot and resolve operational hurdles when encountered and adapt protocols as necessary * Collaborate across CMC functions to optimize bioprocess parameters for the production of difficult-to-manufacture biologics * Execute high-throughput fed batch and batch experiments and perform data analysis of the same * Able to maintain a "can-do" attitude to complete innovative projects while being flexible in work priorities based on business needs * Perform tasks with rigorous attention to detail consistently. Prioritize tasks and contribute to a highly motivated and productive team with a sense of urgency and desire to meet project timelines * Accurately document, critically analyze/interpret data and communicate the results promptly through various electronic means * Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials * Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 50Ibs. * Strong interpersonal skills to thrive in a team environment Experience Required / Qualifications Needed: * BS in Biological Sciences or Chemical/Biochemical Engineering or related field with typically 0-3 years of industry experience; or, MS with no additional experience * Prior experience in bioreactor operation and cell culture media preparation is a must * Industry experience in sterile fermentation techniques preferably mammalian cell culture * Experience in single use mammalian cell culture tools employed in bioprocess development, including but not limited to deep well plates, shake flasks, ambr250s, stirred tank reactors * Excellent aseptic techniques and familiarity with principles of sterilization/disinfection. * Familiar with general troubleshooting techniques and implementation of quality controls in developmental lab * Experience with process development, optimization, and troubleshooting * Experience in setting up high throughput experiments in both fed batch and batch modes, and comfortable with automation and manual operation when needed. * Comfortable with practical considerations needed to successfully scale up conditions tested in high throughput systems to larger scales * Excellent communication skills and experience using collaborative cloud-based technologies to in a hybrid working environment. * Basic knowledge on biological data collection and analysis tools (GraphPad Prism, HPLCs, Blood gas analyzers, metabolite analyzers) and computer applications such as MS Word, MS Excel and MS PowerPoint. * Able to maintain instrumentation, inventory and cleanliness of a developmental lab to create a safe, effective and efficient scientific working environment. * Familiarity with the use of single use mammalian cell culture technologies such as deep well plates, shake flasks, ambr250s, stirred tank bioreactors What are the top 3-5 skills, experience or education required for this position? 1. Time management 2. Adaptable ability 3. Communication 4. Familiarity with solution prep 5. Some exp. with aseptic technique (can be from course) Our role in supporting diversity and inclusion As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.

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