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Scientist, Engineered Stem Cells
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- Our first program centers on JSP-191, a highly specific monoclonal antibody to clear diseased hematopoietic stem cells prior to transplantation while avoiding the toxicity associated with chemo-radiation.
- This position's focus will be to develop technologies around genetic modification of stem cells (mRNA, CRISPR, LNPs, etc
- Design, execute, and analyze preclinical research studies focused on engineering stem cells, and spanning molecular biology and cell biology
- Develop in vitro cell-based assays (cell culture, gene editing, flow cytometry, high content imaging, cytokine profiling, cytotoxicity, proliferation, etc.)
- Perform molecular cloning experiments (PCR, capillary electrophoresis, Gibson assembly, bacterial transformation, screening, plasmid preparation, sequencing, etc.)
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