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Scientific Director - Oligonucleotides Chemistry - Synthetic Molecule Design & Development (SMDD)
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Full-time
- The scientist will collaborate with a growing team comprised of chemists, analysts, and engineers aimed at development and optimization of existing methods and exploration of novel synthetic approaches to oligonucleotides and their conjugates as well as oligonucleotide purification, isolation, and formulation.
- Developing and working with external contract manufacturing organizations (CMOs) to support external oligonucleotide synthesis, tech transfer and campaign execution will be an important aspect of this role.
- Bring an extensive knowledge of oligonucleotide development to SMDD and use this expertise to grow internal capabilities through coaching, mentorship, and leadership.
- Provide examples of novel contributions to chemical design and mechanism-based problem solving as part of project driven goals such as total synthesis, novel methodology development and oligonucleotide synthesis.
- Possess deep understanding of the external global regulatory climate and emerging requirements; ability to address key CMC regulatory questions that enable clinical studies and support marketing authorization applications.
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