Agilent

The world's most revolutionary biopharma companies are partnering with Agilent Technologies to advance the next frontier of medicine.. Documents analyses by completing experiment notebooks and records; implementing process chemistry applications and analyzing results of new oligonucleotide synthesis and purification methods and processes. Executes Design of Experiments (DOE) and Proven Acceptable Range (PAR) experiments to support design space understanding and process validation as they relate to oligonucleotide synthesis, process chromatography, and other purification and isolation techniques. Improves job knowledge by understanding emerging trends in oligonucleotide analytical methods and synthesis development; reviewing professional and technical publications; establishing personal networks and benchmarking state-of-the-art practices. Previous knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization is advantageous

process development

Job Description

The world's most revolutionary biopharma companies are partnering with Agilent Technologies to advance the next frontier of medicine. Agilent continues to invest in the capacity and expansion of its Colorado operations. Join our team of professionals dedicated to the development and commercialization of nucleic acid therapeutics for life-changing, life-saving medicines.

Position Responsibilities:

Understands product requirements by studying and implementing oligonucleotide project objectives and targets related to engineering and chemical requirements
Assists project development by developing synthetic routes, methods, and techniques in preparing, separating, purifying, analyzing, quantifying and resolving oligonucleotide process components and objectives
Maintains process compliance integrity by adhering to standard operating procedures (SOP's) and current good manufacturing practices (cGMP) as appropriate
Documents analyses by completing experiment notebooks and records; implementing process chemistry applications and analyzing results of new oligonucleotide synthesis and purification methods and processes
Sets-up and operates laboratory equipment by following operating instructions; troubleshooting instrumentation and method issues. Applies laboratory experience in chemistry and separations to issues of process optimization, scale-up and laboratory process transfer to mid and kilo scale GMP manufacturing
Executes Design of Experiments (DOE) and Proven Acceptable Range (PAR) experiments to support design space understanding and process validation as they relate to oligonucleotide synthesis, process chromatography, and other purification and isolation techniques
Assists with the preparation of milligram to gram quantities of active pharmaceutical ingredient (API) to support early-stage (Pre-clinical) development and toxicology studies
Helps with the preparation of process descriptions and the writing of technical reports to support internal technology transfer into manufacturing and support in preparation of client CMC submissions
Improves job knowledge by understanding emerging trends in oligonucleotide analytical methods and synthesis development; reviewing professional and technical publications; establishing personal networks and benchmarking state-of-the-art practices

Qualifications
Bachelor's or Master's Degree in chemistry, chemical engineering, science or equivalent or a combination of education and or experience
Post-graduate, certification, and/or license may be required
2+ years relevant experience for entry to this level with preference to experience in a pharmaceutical environment
Previous knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization is advantageous
Detail-oriented and can perform technical duties following standard operating procedures and general laboratory safety rules
Ability to work both independently and in a team setting on a variety of projects and use individual discretion to meet required project objectives and deadlines
Excellent math, documentation, communication and operational troubleshooting skills
Requires general proficiency with tools, systems and procedures to accomplish job

#LI-DT1

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email job_posting@agilent.com or contact +1-262-754-5030.

For more information about equal employment opportunity protections, please visit www.agilent.com/en/accessibility.

Pay Range
$70,720.00-$110,500.00
The salary range for this position may differ based on your actual work location.

Eligible for Company Car
No

Benefits in Brief

Travel Required
No

Schedule
Schedule:Full time

Shift
Day

Duration
No End Date

Job Function
R&D
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