BridgeBio Pharma

Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.. The Research Associate will execute, analyze, and report results for biological assays for preclinical program.. Laboratory operations related to enzyme activity and inhibition.. Education requirementBachelor’s or Master’s degree in Biochemistry, Genetics, Molecular Biology or Pharmacology. Skills Immunoassay and biochemical assayLaboratory experience with Western Blotting and SDS-PAGE is a must.

research associate

Eidos Therapeutics, an affiliate of BridgeBio Pharma, is a Phase 3 developmental-stage biopharmaceutical company focused on addressing the large and growing unmet need in diseases caused by transthyretin, or TTR, amyloidosis, or ATTR. We seek to treat this well-defined family of diseases at their collective source by stabilizing TTR. Our investigational product, acoramidis (AG10), is an orally administered small molecule designed to potently stabilize TTR, a potentially best-in-class treatment aiming to halt the progression of ATTR diseases. BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs. Our focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zurich, Switzerland, and are expanding across Europe. The Research Associate will execute, analyze, and report results for biological assays for preclinical program.This will be a contract position. <h3>Responsibilities </h3><ul><li>Laboratory operations related to enzyme activity and inhibition.Planning and execution of experiments to measure inhibitory activity of small molecule drug candidates against target proteolytic enzymes </li><li>Adhere to company standards and compliance in current industry standards and practices </li><li>Adhere to safety regulations for handling and disposing of human plasma/serum and reagents </li><li>Proper maintenance of laboratory notebooks and forms in accordance with company policies and practices. Routine maintenance, and upkeep of laboratory </li> </ul>No matter your role at BridgeBio, successful team members are: <ul><li>Patient Champions, who put patients first and uphold strict ethical standards </li><li>Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset </li><li>Truth Seekers, who are detailed, rational, and humble problem solvers </li><li>Individuals Who Inspire Excellence in themselves and those around them </li><li>High-quality executors, who execute against goals and milestones with quality, precision, and speed </li> </ul><h3>Education, Experience & Skills Requirements </h3><ul><li>Education requirement<ul><li>Bachelor’s or Master’s degree in Biochemistry, Genetics, Molecular Biology or Pharmacology </li> </ul> </li><li>Enzyme assays<ul><li>4-5 years in Pharmaceutical Diagnostic in R&D or GLP environment </li><li>Knowledge of GLP practice desired </li> </ul> </li><li>Skills Immunoassay and biochemical assay<ul><li>Laboratory experience with Western Blotting and SDS-PAGE is a must. Basic knowledge of immunoassays and fluorescence biochemistry is preferred. Hands on experience in protease assays in plate format with colorimetric or fluorometric detection is desired. </li><li>Strongly self-motivated individual with attention to detail </li><li>Good time-management skills </li><li>Good interpersonal skills, flexibility and works well independently and within a team environment </li> </ul> </li><li>Travel<ul><li>Not required except physical laboratory presence during work week </li> </ul> </li><li>This is not a remote work position </li> </ul><h3>What We Offer </h3><ul><li>Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts </li><li>A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak </li><li>An unyielding commitment to always putting patients first. Learn more about how we do thishere </li><li>A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science </li><li>A place where you own the vision – both for your program and your own career path </li><li>A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game </li><li>Access to learning and development resources to help you get in the best professional shape of your life </li><li>Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs) </li><li>Flexible PTO </li><li>Rapid career advancement for strong performers </li><li>Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time </li><li>Commitment to Diversity, Equity & Inclusion </li> </ul> At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.#J-18808-Ljbffr

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