Upvote
Downvote
Principal Scientist, Discovery - Ocular Genetics
Share Job
- Suggest Revision
- Johnson & Johnson is recruiting for a Principal Scientist, Discovery - Ocular Genetics located in Cambridge, MA.
- Human genetics offers an opportunity to bridge a translational gap in drug discovery by anchoring the identification of target mechanisms in human disease biology thus improving the probability of pursuing targets that will ultimately be efficacious.
- The sequencing of large-scale biobanks, GWAS and mendelian genetics have generated an unprecedented resource for discovery and interpretation that can aid drug development.
- The application of transcriptomics, metabolomics and circulating proteomics across genetically characterized human cohorts has further enabled the interpretation of variant effects on mRNA, metabolite or circulating protein which can be harnessed for biomarker identification.
- The Principal Scientist in this role will develop and apply methods for the integration of GWAS summary results with other types of data e.g. Metabolomics/mQTL, eQTL, functional genomic annotations, gene networks, estimation/partitioning of heritability, Mendelian Randomization to understand causal direction, and fine mapping.
Active Job
Updated TodaySimilar Job
Relevance
Active