The Chan Zuckerberg Biohub, Inc

Associate Bioinformatics Scientist/Computational Biologist. Developing workflows to process and analyze single-cell multi-omics datasets (both in-house and publicly available datasets) to gain a holistic view of transcriptional regulation during zebrafish development. genetic perturbations on developing zebrafish at whole organism scale - Zebrahub v2.0 ( ).. B.S. or M.S. degree in Data Science, Computational Biology, Bioinformatics, or a related discipline. Familiarity with the concepts of molecular biology, cell biology, genomics, and biostatistics

computational biologist

The Opportunity The Data Science platform at CZ Biohub SF( https://www.czbiohub.org/data-science/ ) is seeking an Associate Bioinformatics Scientist/Computational Biologist to join a fantastic team of computational biologists and data scientists. We develop computational methods, pipelines, and software that enable Biohub’s research across quantitative cell biology and infectious disease. In this position, you will closely collaborate with biologists and engineers from Biohub research groups such as the Royer group ( https://www.czbiohub.org/royer/ ) and the Balla group ( https://www.czbiohub.org/balla/ ). Potential projects include: Developing workflows to process and analyze single-cell multi-omics datasets (both in-house and publicly available datasets) to gain a holistic view of transcriptional regulation during zebrafish development Participating in data integration across multiple modalities (single-cell genomics, microscopy, etc.) to create a resource for the broader scientific community. Prime examples are our previous work, such as Zebrahub ( https://zebrahub.ds.czbiohub.org ) and OpenCell ( https://opencell.czbiohub.org ). Contributing to interactive web portals for in silico genetic perturbations on developing zebrafish at whole organism scale - Zebrahub v2.0 ( https://zebrahub.ds.czbiohub.org ). This is an excellent opportunity to do both research and engineering at the intersection of bioinformatics, infectious diseases, and cell biology. You will Contribute to scientific discovery via analysis of single-cell multi-omics datasets (transcriptomic, epigenomic, and/or proteomic) Participate in developing bioinformatics tools and web portals Optimize and execute data processing pipelines in an HPC environment Partner with biologists to conduct data mining and exploratory data analysis Author publications and disseminate research discoveries to the scientific community You have Essential – B.S. or M.S. degree in Data Science, Computational Biology, Bioinformatics, or a related discipline A minimum of 2 years of experience with scientific programming languages and data science workflows (e.g. Python, R, Git, UNIX command line, etc.) Familiarity with professional software development best practices (documentation, version control, etc.) Proven ability to implement exploratory data analysis and statistical inference in the context of scientific research A collaborative, team-focused mindset coupled with outstanding communication skills, and the ability to work in an agile environment Nice to have - Experience with single-cell RNA-seq data analysis and/or other multi-dimensional omic data modalities Familiarity with the concepts of molecular biology, cell biology, genomics, and biostatistics Experience with high-performance computing (HPC) clusters and job schedulers such as Slurm Enthusiasm for systems biology and development of open-source software Experience with using machine learning algorithms to extract insights from complex datasets Research experience in academic laboratories is highly preferred The Chan Zuckerberg Biohub requires all employees, contractors, and interns, regardless of work location or type of role, to provide proof of full COVID-19 vaccination, including a booster vaccine dose, if eligible, by their start date. Those who are unable to get vaccinated or obtain a booster dose because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date. Compensation $72,000 - $99,000 #J-18808-Ljbffr

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