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BS/MS in Analytical Chemistry, Biochemistry or Chemical Engineering. The scientist will assess nucleic acid and protein pharmaceuticals in biological extracts using liquid chromatography (LC), and electrophoresis (CE.
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UNP’s approach couples machine learning-based in silico tools with massively parallel peptide chemistry to enable the discovery and rapid optimization of highly non-natural macrocyclic peptides aimed at extracellular targets, undruggable intracellular oncology targets, and beyond.
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Conduct deep learning experiments to enhance model performance or introduce new functionalities, such as loop engineering and structure prediction of protein-protein complexes. Knowledge in physics, mathematics, molecular biology, chemistry, etc.
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Understanding of the basic principles of protein chemistry and/or drug product process is required. This position is required to conduct studies to enable Drug Product characterization activities, including combination products at high protein concentration, as well as commercial products.
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Strong understanding and hands-on experience with proteomics workflows including targeted, DDA, DIA and TMT applied to single protein analysis, affinity purifications, and global profiling, Expert competency in one or more of the following: Quantitative Proteomics Workflows: Absolute and relative quantification of peptides and proteins from biological matrices.
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Will perform routine cellular and molecular assays (e.g., transformation, miniprep, maxiprep, RNA, DNA and protein preparation, cDNA synthesis, qRT-PCR, transfection, packaging of viral vectors, ELISA, Western Blotting, etc.
$51,839 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Understanding of assay development, biotherapeutics development is a plus. The job entails experimental work on various aspects of Drug Product characterization, including formulation development, safety risk assessment of excipients as well as process reagents, extractables and leachables, in use compatibility studies for intravenous and subcutaneous administration, process development to support drug product manufacturing support, particulates testing.
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Projects may include developing cheminformatics tools and algorithms; large-scale virtual screening and protein-protein docking; creating scalable on-demand ML inference infrastructure; developing scalable chemical databases; automation of modeling, analysis, and visualization of simulations; and a range of similar tasks integral to achieving our mission of becoming the leading AI-enabled drug discovery in the field of induced proximity.
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The Department of Chemistry and Biochemistry is a nationally ranked, research-intensive unit with over $25 million dollars of research-grade instrumentation including spectrometers (nuclear magnetic resonance, mass, optical, x-ray), chromatographs (gas and liquid), vacuum equipment (pumps, chambers) and laboratory equipment (analytical balances, centrifuges, motors, refrigeration and other temperature-controlled devices, etc.
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Good written/oral communication skills in English, and experience in cellular and molecular biology techniques (e.g., flow cytometry, RNA isolation, protein analysis methods), rodent models and cell culture in vitro models are highly desirable.
$50,000 - $60,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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PhD/MS degree or equivalent industry experience in Materials Science, Food Science, Chemistry, Chemical Engineering, or related fields with 8+ years of broad technical, experience. Leadership of the protein sub-function includes global research in support of R&D efforts, regulatory compliance, product quality and customer testing issues.
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The research scientist will collaborate with principal investigators and will be responsible for performing experiments as part of, but not limited, to our funded projects (cell culture, molecular biology, protein chemistry, flow cytometry, animal models etc.
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PhD required, preferably in a field related to theoretical or computational chemistry, chemistry, biophysics or a related discipline. Strong background in computational chemistry and HPC computing.
$70,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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We are seeking a motivated and curious Associate/Sr. Associate scientist to join the Protein Science team, where you will contribute to the development of a new drug delivery platform and clinical program pipeline by preparing, purifying, and characterizing bioconjugates, integrating knowledge of chemistry and biology to enable targeted drug delivery.
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Contribute to the design, development, and optimization of surface chemistry and bioconjugation methods for immobilizing peptides on a semiconductor chip for single molecule protein sequencing.
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protein chemistry jobs in New York, NY
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