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This position will play a key role in tying together automated laboratory liquid handling systems, robotic workcell automation and robust industrial automation systems into a new NGS-based clinical diagnostic system capable of running millions of patient samples per year.
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Testing performed: HLA Flow PRA screen; Luminex Single Antigen (LSA) HLA Class I & II; Flow cross-matching; ELISA; cell isolation and preservation from peripheral blood and donor tissue specimen; DNA extraction, purification, and quantitation; various molecular typing techniques to include Next-generation sequencing (NGS), RT-PCR, and low to intermediate resolution SSO/SSP typing.
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Experience with cutting-edge technologies, including PCR, NGS, immunoassays, microscopy, and related methodologies. We are supported in this mission by top Silicon Valley and New York venture firms that are leaders in the healthcare space with extensive experience in supporting precision medicine companies such as Foundation Medicine and Guardant Health.
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Preferred Qualifications Experience in advanced cancers and/or NGS testing. Position Overview The Senior Medical Science Liaison III will act as a medical/clinical educational liaison to key departments within Exact Sciences and will be a member of the medical science liaison (MSL) group within the Precision Oncology business unit.
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Develop, configure, program, and troubleshoot large scale automated solutions for novel NGS-based clinical diagnostic testing in a regulated environment. Experience developing control systems using PLCs or other I/O infrastructure (e.g. Allen Bradley, Beckhoff, Siemens, Labview, Arduino, etc.
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Develop and optimize analysis workflows to analyze NGS data, including both whole genome sequencing (WGS/WES), targeted sequencing, and bulk/single cell RNA Seq. Demonstrated experience in the field of computational biology, CRISPR off target genomics, cancer genomics, and/or single-cell genomics.
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BioSkyrb Genomics is a biotechnology company headquartered in Durham, NC. We develop advanced technology products that enhance next-generation sequencing (NGS) workflows in both the research and clinical space, using our proprietary genome amplification system.
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Preferred one year of work experience as Medical Laboratory Scientist (MLS)/Medical Laboratory Technician (MLT), previous HLA experience, and/or comparable Immunology, genetics, or molecular diagnostics research.
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Complete quality review of all samples within the NGS workflow from extraction to sequencing. Provide daily oversight of a cutting-edge molecular workflow to provide high-quality next-generation sequencing data with rapid turnaround times, including tumor genomic, germline genomic, and transcriptomic sequencing.
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Stay updated with clinical literature in NGS, especially in Pathology and Oncology. Strategize for evidence generation in Pathology/Oncology using NGS, focusing on Clinical Validity/Utility studies to be performed in NA.
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Certification by one of the following accrediting agencies desired: CHT (ABHI), CHS (ABHI), MB (ASCP), MLS/MLT (ASCP) or categorical MT (NCA), MT (AMT), MT (HHS or HEW). A strong background in Flow Cytometry, Immunohematology, Immunology, and/or Molecular Biology techniques is preferred.
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Knowledge of next generation sequencing (NGS) and/or PCR. Knowledge of next generation sequencing (NGS) and/or PCR. 3+ years' handling a wide variety of responsibilities for CLIA QA for a molecular diagnostics company.
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Understanding of molecular biology techniques such as DNA/RNA extractions, PCR, qPCR, and NGS. Understanding of molecular biology techniques such as DNA/RNA extractions, PCR, qPCR, and NGS. Enrolled in a BS program majoring in molecular and cellular biology, genetics, biochemistry, neuroscience and/or related field.
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Experience with NGS library preparation workflows and molecular biology techniques. Experience with developing and optimizing NGS assay protocols. Prototype, optimize, and implement new NGS-based assays for early cancer detection.
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Knowledge of bioinformatics and next-generation sequencing (NGS) technology is a plus. Knowledge of bioinformatics and next-generation sequencing (NGS) technology is a plus. Biomarker is a biotechnology company that specializes in technology services, medical genetic testing, and bio-cloud platforms.
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ngs job in Cary, NC
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