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The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp®, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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A leading biotech company focused on developing novel therapeutic products is looking for a talented Analytical Scientist with a strong background in cell and gene therapies to join their team.
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You will collaborate with multidisciplinary teams, apply your expertise in medicinal chemistry, and contribute to the advancement of the company's therapeutic programs. To be considered for this role you will need to have industry experience with a drug discovery team, utilising your medicinal chemistry PhD. You will need to have knowledge of modern synthetic organic chemistry techniques and purification methods and ideally a good understanding of ADME.
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On our client's behalf we are seeking a highly skilled and motivated Medicinal Chemist to join a renowned drug discovery team. Newton Colmore is a specialist recruitment agency that is dedicated to the biotech, drug discovery and medical devices markets, in the UK and the US. Our consultants have been honing their craft for a combined 25 years and over that time have built extensive networks.
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This is a unique opportunity to creatively contribute to many in vitro and in vivo aspects of therapeutic antibody discovery. We have developed an innovative new platform for the rapid, high throughput discovery of immune-oncology targets and therapeutic antibodies to combat ovarian cancer.
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Job Overview: This job is seeking a drug discovery leader with expertise in the anti-fungal therapeutic area, who has made substantial contributions to target identification and drug discovery efforts, and has experience in assay and in vivo model development.
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The Executive Director, Biostatistics has extensive experience in the pharmaceutical industry to independently lead a therapeutic area biostatistics team (e.g. Neurology, Metabolics, Hematology/Nephrology, Metabolism or other) to deliver project, tools and/or technical level activities related to design, delivery and interpretation, advises statisticians across business units to prepare for high level internal governance committees and/or regulatory submissions.
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The Senior Director, Biostatistics will independently perform highly scientific statistical functions in support of a company therapeutic area or areas on new and complex issues. NDA/MAA experience and direct dealings with US or European regulators.
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Develop and execute efficient strategies for target identification, prioritization and validation; review, propose, initiate, and implement new pre-clinical therapeutic antibody drug discovery and development programs in the field of Immunology and Inflammation.
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In the past decade, as the fields of proteomics and metabolomics have developed as leading techniques for determining biomarkers for disease presence, progression and the monitoring of therapeutic response, CIL has worked closely with industry leaders and researchers to provide the stable isotope-labeled tools needed for improved quantitation and qualification of complex biological systems.
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Develop collaborative relationships with Key Opinion Leaders (KOLs) in therapeutic areas of interest to establish foundational preclinical data sets providing new insights and pathways for therapeutic intervention.
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Supports internal teams by providing literature reviews and medical and scientific information related to argenx therapeutic areas. Perform critical analysis and synthesis of internal/external literature related to argenx products and therapeutic areas of focus.
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Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology, with the aim of helping to optimize clinical trials investigating the treatment of IBD. We use advanced machine learning and computer vision to interpret endoscopic videos along with other types of data, helping clinicians better assess patients with potential GI problems.
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This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells.
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Integrate data to provide a detailed understanding of the pharmacology of therapeutic proteins to enable understanding of in vitro MOAs and in vivo correlates of efficacy. Deep pharmacology experience, particularly on the design of PK/PD and toxicology studies to define therapeutic index.
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therapeutic job in Cambridge, MA
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