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We are seeking a Research Engineer, in the Traverso Lab at Brigham and Women's Hospital with a background in analytical chemistry. Design automated liquid handling programs for bioanalytical sample preparation, including: protein precipitation, solid phase extraction (SPE), and supported liquid extraction (SLE.
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Deep experience with peptide and protein chemistry with emphasis on optimization of in vivo properties. Leverage vast knowledge in peptide chemistry, oligonucleotide chemistry and conjugation chemistry to discover, engineer or improve performance of existing and future compounds.
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Expertise and hands on experience in liquid chromatography, protein chemistry and mass spectrometry of protein molecules, including glycoproteins, experience in LC and LC-MS method development and qualification.
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The candidate will have the opportunity to lead multi-disciplinary drug discovery and preclinical teams as targets progress and will be expected to work seamlessly with colleagues across discovery research, chemistry, preclinical pharmacology, toxicology and analytical development.
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Protein quantification techniques (e.g. Western, ELISA, MSD, Mass Spectrometry, Luminex-based assays) Currently enrolled in undergraduate or graduate program with a focus on Biology, Biochemistry, Chemistry, Immunology, Cell Biology, Molecular Biology, or other related Life Science field.
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Those with a strong ML background but without the necessary protein/chemistry background are welcome to apply) If you have a solid foundation in machine learning and a keen interest in peptide/protein engineering and design, you could be pivotal in our journey.
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Ventus Therapeutics is a clinical-stage biopharmaceutical company deploying leading-edge structural biology and computational chemistry tools to create novel small molecule medicines for challenging targets in immunology, inflammation, and neurology.
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Strong working knowledge of protein chemistry, characterization and biophysical methods. Associate Scientist, Protein Biochemistry. Experience with a subset of techniques such as: protein labeling/biotinylation, ELISA/MSD, analytical HPLC, light scattering methods (MALS/DLS), DSF, SPR (Biacore) or other methods of measuring binding kinetics and affinity, Pymol.
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Bachelor degree in organic chemistry or biochemistry/chemical biology with undergraduate research experience in synthetic methodology, total synthesis, peptide/protein chemistry, oligonucleotide chemistry, or synthetic/conjugation chemistry.
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Ph. D. in Proteomics, Molecular Cellular Biology, Analytical Chemistry or a relevant field or M.S. degree in a relevant field +3 year industry experience. Excellent knowledge and practical experience with preparation techniques of proteomics sample, nanoLC-MS/MS workflows, data processing for large-scale protein characterization, and quantification applications.
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REQUIRED: bachelor's degree that included coursework in biology, biochemistry, and/or chemistry; experience with molecular cloning, protein purification, or mammalian tissue culture. The work will involve molecular cloning, protein expression, protein purification, and mammalian tissue culture.
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Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design of protein editing chemistries. About FL94FL94 Inc., is a privately held, early-stage biotechnology company pioneering Protein Editing.
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The top candidates will have several years of experience in industry and across a diversity of biochemistry disciplines such as protein chemistry, protein expression & purification, biophysics, enzymology, and structural biology.
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Reporting to the Associate Director of Analytical Development, the Scientist will be responsible for the development of biophysical and analytical chemistry methods to further gene therapy products throughout clinical development, as well as performing BLenabling characterization studies.
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Similar experience in protein purification and chromatography experience will be considered. Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering or equivalent and relevant formal academic / vocational qualification.
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protein chemistry jobs in Cambridge, MA
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