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With your passion for process development, and a particular interest in downstream product recovery and purification, you'll help to design, develop, and deploy product recovery and purification processes for a variety of products across several scales and sites.
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The Manager, Packaging Engineer will provide technical expertise associated with pharmaceutical packaging and serialization programs for Blueprint Medicine's clinical and commercial products, including packaging design and specification, equipment/tooling design, qualification and validation, artwork & labeling, material selection and testing.
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Downstream purification of biologics including chromatography separations and filtration operations. essential for success., Cell culture, microbial fermentation, Chromatography design, use of QbD and.
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Design processes for the purification and formulation of sterile, injectable, LVV-based gene therapy clinical trial materials. Hands-on experience with end-to-end biologics purification process development or MSAT, experience with LVV, AAV, or gamma-retroviral vectors strongly preferred.
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Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.
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Downstream Process Development: The position will provide opportunities to take ownership of an internship project and contribute to the development of commercially relevant manufacturing processes.
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Experience in Investment Accounting and/or Investment/Treasury Operations for derivatives with a foundational understanding of the upstream processes and impacts to downstream accounting and reporting.
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Significant Hands on experience in design and development of custom solutions on the Force.com platform including significant work in Apex, VisualForce, Lightning, application integration patterns using Mulesoft and other ETL tools.
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Familiar with battery product development process, key milestones and deliverables, including systematic interactive development content with upstream and downstream products. Assisting in product design, testing and verification, project summary, and data archiving.
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Performing and leading all aspects of new product introductions, technology transfer, experimental design, equipment commissioning, and participate in equipment design. Solid knowledge of upstream and/or downstream, as well as a general knowledge of the associated analytical, and media/buffer preparation techniques.
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The incumbent is responsible to ensure design/configuration takes into consideration of upstream/downstream business processes and data quality impact. Work collaboratively across the GHR teams to understand business strategies, program design initiatives and turn them into clear business requirements.
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Leverage DFM/DFA skills to influence product decisions and communicate the downstream operational impacts of design. Ramp new sourcing efforts in response to changes in products, supply chain design, and manufacturing locations.
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Design, Build, Test, and Deploy Workday Integration solutions using Custom Reports, EIB, Core Connectors, Document Transformations, XSLT and Workday Studio. Develop and maintain integration between Workday and external payroll system (UKG Pro), benefits providers, learning content providers, stock and retirement providers, as well as internal downstream systems.
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Apply advanced solar engineering technical knowledge to minimize downstream design and installation issues. Design responsibility includes but not limited to new homes and residential retrofit.
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This implies providing design for integration with all upstream and downstream processes. Knowledge of Integration with all other upstream and downstream engineering / automotive industries business processes.
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downstream design jobs in Cambridge, MA
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