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Minimum of B.S. in biology, bioengineering, biochemistry, or equivalent and 3-5 years of relevant experience in the biotech or pharmaceutical industry. They will collaborate with various internal functions including Analytical, Upstream/Downstream Manufacturing, Quality Control, Quality Assurance, Regulatory, and Supply Chain to ensure best practices are implemented and followed at external contract manufacturing and testing labs, and internally at Leap Therapeutics.
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Ring is seeking a Scientist I to join the Downstream Process Development team to help establish and develop our in vitro viral vector platform. PhD (preferred) or BS + 8 years or MS + 6 years relevant experience in bioengineering, chemical engineering, biology, virology, biochemistry or related field.
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Preparing samples for Next-Generation Sequencing (NGS) and other downstream analyses, ensuring the accuracy and integrity of our data. Currently pursuing a BS or MS in biology, biochemistry, biomedical engineering, or a related field of study.
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Established sales history and relationships with the downstream process development group within key biopharmaceutical accounts in the aforementioned territory would be highly desirable. Selling Thermo Fisher's downstream chromatography products (POROS Chromatography and CaptureSelect Affinity resins and columns) into process development and clinical/commercial manufacturing groups within biopharma accounts.
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Exceptional Ph. D. in immunology, bacteriology, virology, molecular biology, biochemistry or biophysics ideally with industry experience. Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.
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Lead an integrated process development team across upstream and downstream functions for mRNA production. Ph. D. in Chemical/Biomedical Engineering, Biochemistry, or a related discipline with 8+ years of relevant industrial experience, M.S. with 10+ years, or B.S with 12+ years.
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The incumbent will be part of the Viral Vector Product Development Leadership Team in defining overall strategy, team growth, budgeting, and providing expertise to project team on all aspects of downstream process development.
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Or equivalent in Pharmaceutical Sciences, Bio/Chemical Engineering, Biochemistry, Molecular Biology, or related discipline. activities for Alexion’s AAV production platform. or equivalent in Pharmaceutical Sciences, Bio/Chemical Engineering, Biochemistry, Molecular Biology, or related discipline.
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Requirements: B.S. or B.A. equivalent in Chemistry, Biochemistry or related field with 0-1 yrs general laboratory experience. This role will involve synthesis, downstream processing, and characterization of the synthetic oligonucleotides using state-of-the-art equipment.
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And with proteins expressed in mammalian cells with oversight of both upstream and downstream process development. Academic/PhD degree in Biochemistry, Biology, Bioengineering, Immunology, or related discipline.
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Hands on experience in biochemistry techniques such as protein expression, gel electrophoresis, protein quantification assays, and enzyme kinetics. Your primary responsibility is to perform hands-on development of purification and characterization methods for nucleic acids such as mRNA and circRNA, with the ultimate goal of generating therapeutic grade material for in-vitro downstream assays and pre-clinical in-vivo studies.
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BA/BS or MS in molecular biology, biochemistry, metabolism, or related field with 2-5 years of experience in drug discovery research. Supervise the execution of pharmacology studies at CROs and perform in-house downstream analysis to support drug discovery program needs.
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Perform routine production activities such as upstream and downstream processing, purification, and formulation. Bachelor's degree in Biotechnology, Biochemistry, Molecular Biology, or related field.
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Ph. D. in Biochemistry, Bioengineering, Biophysics, Molecular Biology, or related field, with at least 5–10 years postgraduate experience in an academic or industry setting. Working collaboratively with selection scientists, protein scientists, biochemists, and biologists, you will develop and optimize workflows to optimize antibody potency, selectivity, and format at the early-stage optimization and downstream development phases of antibody drug discovery.
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Extensive experience (including hands-on experience) within specific areas of biologics process development is required (i.e. cell line development, cell culture (upstream) process development, or purification (downstream) development) with an interest in learning and expanding responsibilities across all areas of biologics process development.
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downstream biochemistry jobs in Cambridge, MA
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