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In vitro Transcription (IVT) and RNA characterization by gel electrophoresis, nanodrop and endotoxin testing. Maintaining reagent, DNA, RNA and protein inventory. Transient cell culture techniques such as transfection, cell number and viability monitoring, cell lysis and protein harvest Purification of proteins using liquid chromatography techniques.
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Explore advancing technologies such as spatial transcriptomoics, combined single-cell ATAC and RNA multiomics, and pooled CRISPR screening. Department/Area Stem Cell and Regenerative Biology Position Description The Arlotta lab at HSCRB is working to identify the cellular and molecular pathways disrupted in brain disorders such as schizophrenia and autism, by utilizing recent advances in genetics and genomics.
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Basic wet lab skills, including but not limited to, molecular biology and biochemistry techniques such as DNA and RNA extraction, lysate preparation, qPCR, protein quantification, Western blot/WES/JESS, and ELISA is preferred.
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The Clinical Laboratory Technologist will be responsible for performing high-complexity molecular testing according to established SOPs, including DNA and RNA extractions, NGS library preparation, hybridization-based enrichments, and next-generation sequencing.
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About AlnylamAlnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases.
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O Sample prep for the extraction of biomolecules such as nucleic acids (DNA and RNA) and protein, downstream processing and analysis, using Covaris’ proprietary AFA™ technology. Have experience in basic molecular biology techniques (PCR, electrophoresis, nucleic acid or protein isolation and purification.
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Conduct molecular biology assays such as DNA and RNA isolation, PCR and qPCR, western blot etc. The successful candidate will work with his/her supervisor to design, plan and conduct molecular biology and cell culture experiments to evaluate strategies to improve AAV production platforms through expression vector modification and/or host cell line engineering.
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The Senior Director of Technical Innovation requires a combination of CMC technical expertise (e.g. gene therapy, RNA, gene editing), effective communication, business and strategic acumen. The Senior Director of Technical Innovation requires a combination of CMC technical expertise (e.g. gene therapy, RNA, gene editing), effective communication, business and strategic acumen.
$270,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Primary responsibilities would include but not limit to molecular cloning, in vitro transcription, small-scale RNA purification, and DNA/RNA QC. The ideal candidate will work in an interdisciplinary team to support the development of self-amplifying mRNA vaccine.
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Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases.
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Our RNA medicines platform, PRISM, combines. modalities includes editing, splicing, RNA interference and antisense silencing, RNA medicines to transform human health. Our toolkit of RNA targeting.
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RNA extraction from in vivo samples such as blood or tissue and downstream statistical bioinformatics analyses (not required experience, but a plus!) At Tessera Therapeutics, he leads a team dedicated to advancing LC-MS-based proteomics and RNA bioanalysis to support preclinical studies for Gene Writing and Rewriting Therapeutics.
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Experience with molecular and cellular biology instruments and techniques, e.g., DNA/RNA/Protein purification, ddPCR and qPCR, flow cytometry, Western blotting, MSD, ELISAs, TapeStation, JESS. Experience in development and optimization of bioanalytical assays relevant to AAV gene therapy pharmacology and safety (e.g. biodistribution, GOI RNA expression and protein quantification, ADA, nAb/Tab, ELISpot.
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Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq. Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq.
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The Associate Director, Packaging Operations & Supply Chain will be the person supporting CMO-lead finished goods labeling, packaging, and 3PL logistics operations management for Sarepta's three commercial RNA products.
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rna job in Burlington, MA
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