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Configuration & Date Management (CM / DM) comprehension and aptitude to develop advanced TDP record set management techniques in PDM. Multi-disciplined support potential in Electrical Computer Aided Design (CAD) design / drafting experience, MentorGraphics design applications (DxDesigner, Valor), DownStream Technologies (BluePrint-PCB), and/or other electrical change comparison software.
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Production experience with proteins expressed and refolded from E. coli and with proteins expressed in mammalian cells with oversight of both upstream and downstream process development. Develop and optimize upstream and downstream processes to generate lead and Development Candidate TCR bispecific and to enable seamless technology transfer to contract manufacturing organizations.
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RNA/DNA/protein extraction, QC and downstream biomarker assays. RNA/DNA/protein extraction, QC and downstream biomarker assays. Sample management and tracking, including the receiving and sending of.
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Here's What You'll Do:Lead right-first-time cGMP manufacturing of cell and gene therapy products including but not limited to aseptic processing, cell isolation, selection, culturing, cryopreservation, upstream processing, downstream processing, aseptic fill finish and final product visual inspection.
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Design, build, and manage robust and reusable data models and transformation pipelines that support a variety of downstream use cases and applications; Demonstrated ability working with downstream stakeholders to understand their requirements and convert those needs into reliable, cost-efficient, and scalable data solutions gained through five (5) years of work experience.
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The individual needs to exhibit a thorough understanding of how a banking operations team is run with knowledge of all allied functions, both upstream and downstream and how they all fit into the larger operating environment of the bank.
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8+ years of relevant experience in Investment Accounting and/or Investment Operations for derivative investments with a foundational understanding of the upstream processes and impacts to downstream accounting and Controllership.
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Priority will be given to candidates experienced in additional stages upstream and downstream of the production process including but not limited to protein engineering, vector design, quality attribute generation, and functional characterization of biotherapeutics.
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Associate Director, Downstream Process Development (Proteins) 2033669. Strong relevant industry experience in downstream process development for proteins. Develop and optimize downstream processes for protein therapeutics.
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Proactively monitor and analyze data quality to ensure accuracy of reporting and downstream impact on other contracted services. Previous experience with insurance claims or Medicare compliance preferred.
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Help maintain a stable, error/incident free Production and test environments for users across diff regions- NA and EMEA, ensure SLAs are upheld and various feeds to upstream and downstream systems are maintained.
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Oversee AI-based document collection and data extraction technology; validate downstream impact to datawarehouse, research management system (RMS), and accounting software. Coordinate with third-party administrator during periodic accounting closes to validate performance, capital activity, and other investment metrics included in our investor reporting and internal analytics.
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Execute downstream contract administration, including Request for Information (RFI's), submittals, meeting minutes, change management, and claims mitigation. Support the Prime Contract, subcontract, client contractor, and supplier invoicing process.
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Lead internal process development, optimization and tech transfer of upstream and downstream process development for clinical development pipeline. Extensive experience selecting and overseeing CDMO’s for tech transfer of protein manufacturing including both upstream and downstream methods.
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Research and resolve transaction, profit and loss, and valuation reconciliations between internal records, investment reporting, third party administrator, banks, and other counterparties. Contribute towards projects including RMS conversion, technology optimization, investment data collection, workflow automation, and more.
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downstream job in Boston, MA
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