{"schemaVersion":"jobsearcher.job.v1","id":"d2b6621bec8465d4117bcb79","url":"https://jobsearcher.com/jobs/d2b6621bec8465d4117bcb79","canonicalUrl":"https://jobsearcher.com/jobs/d2b6621bec8465d4117bcb79","title":"Senior Python Developer Lead","description":"Senior Python Developer And ArchitectProject description Genentech's Research & Early Development group (gRED) excels in understanding the mechanisms of biology that drive disease to develop world-class therapeutics. To do so, gRED analyzes vast amounts of scientific data and creates cutting edge tools to enable data analysis at scale for all scientists.These analyses often involve multiple-step workflows that must be assembled on demand from a variety of stand-alone, command-line tools, and we are looking for a lead architect to develop and execute the next steps in this strategy that allows scientists with novice computational knowledge to collect data, configure analyses using a web UI, and execute multi-step workflows.This system also provides scientists with a common programmatic framework for the management of data and its descriptive metadata, and enables key visualizations of the data using interactive web interfaces. This system powers multiple laboratory workflows across gRED where the raw data that is generated must be processed through a set of different tools before the data can be interpreted. These separate tools must work together in a coordinated fashion at scale. We're searching for a full time Senior Python Developer and Architect to lead the team creating the Bluecopper system.Responsibilities:Design and oversee the architecture of the Bluecopper SystemCollaborate with cross-functional teams to define, design, and ship new featuresWork with Business Analysts to understand functional and non-functional requirements and develop appropriate system architecturesWrite clean, scalable, and efficient Python codeConduct code reviews and provide constructive feedbackTroubleshoot, test, and maintain the core product software to ensure strong optimization and functionalityWork together with DevOps engineers to deploy and maintain the system in a cloud-based environmentMonitor system performance and implement improvements as necessaryMentor the development team and enhance the understanding of best practicesRequired technologies and skills:Python (must have), including the following frameworks/libraries:Experience in developing within a web application framework using SQLAlchemy (e.g. Pyramid)Demonstrated experience in developing APIs to serve both Typescript / Javascript frontend environments and to serve other internal usersMySQL (must have)Gitlab (must have)CI/CD pipelines (must have)Docker (must have)Process orchestration in high-performance computing environments (must have)Building distributed systems (must have)Automated testing - unit, int, e2e, performance, regression (must have)Deployment within a cloud-based environment (e.g. AWS)Jenkins (nice to have)Strong ownership and accountability mindsetFluent in EnglishExcellent communication skillsExperience in working with distributed development teamsExperience in working in a global environmentExpertise in agile delivery in ScrumQuick learnerSelf organized, reliable and precise","company":"Intersources","rawCompany":"intersources","city":"Denver","state":"CO","isRemote":false,"isActive":false,"createdAt":"2026-10-16T14:08:22.084Z","occupations":[{"code":"15-1252.00","title":"Software Developers","slug":"software-developers"},{"code":"15-1299.08","title":"Computer Systems Engineers/Architects","slug":"computer-systems-engineers-architects"},{"code":"15-1251.00","title":"Computer Programmers","slug":"computer-programmers"}],"industries":[{"code":"541512","title":"Computer Systems Design Services","slug":"computer-systems-design-services"},{"code":"541511","title":"Custom Computer Programming Services","slug":"custom-computer-programming-services"},{"code":"513210","title":"Software Publishers","slug":"software-publishers"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Senior Python Developer Lead","description":"Senior Python Developer And ArchitectProject description Genentech's Research & Early Development group (gRED) excels in understanding the mechanisms of biology that drive disease to develop world-class therapeutics. To do so, gRED analyzes vast amounts of scientific data and creates cutting edge tools to enable data analysis at scale for all scientists.These analyses often involve multiple-step workflows that must be assembled on demand from a variety of stand-alone, command-line tools, and we are looking for a lead architect to develop and execute the next steps in this strategy that allows scientists with novice computational knowledge to collect data, configure analyses using a web UI, and execute multi-step workflows.This system also provides scientists with a common programmatic framework for the management of data and its descriptive metadata, and enables key visualizations of the data using interactive web interfaces. This system powers multiple laboratory workflows across gRED where the raw data that is generated must be processed through a set of different tools before the data can be interpreted. These separate tools must work together in a coordinated fashion at scale. We're searching for a full time Senior Python Developer and Architect to lead the team creating the Bluecopper system.Responsibilities:Design and oversee the architecture of the Bluecopper SystemCollaborate with cross-functional teams to define, design, and ship new featuresWork with Business Analysts to understand functional and non-functional requirements and develop appropriate system architecturesWrite clean, scalable, and efficient Python codeConduct code reviews and provide constructive feedbackTroubleshoot, test, and maintain the core product software to ensure strong optimization and functionalityWork together with DevOps engineers to deploy and maintain the system in a cloud-based environmentMonitor system performance and implement improvements as necessaryMentor the development team and enhance the understanding of best practicesRequired technologies and skills:Python (must have), including the following frameworks/libraries:Experience in developing within a web application framework using SQLAlchemy (e.g. Pyramid)Demonstrated experience in developing APIs to serve both Typescript / Javascript frontend environments and to serve other internal usersMySQL (must have)Gitlab (must have)CI/CD pipelines (must have)Docker (must have)Process orchestration in high-performance computing environments (must have)Building distributed systems (must have)Automated testing - unit, int, e2e, performance, regression (must have)Deployment within a cloud-based environment (e.g. AWS)Jenkins (nice to have)Strong ownership and accountability mindsetFluent in EnglishExcellent communication skillsExperience in working with distributed development teamsExperience in working in a global environmentExpertise in agile delivery in ScrumQuick learnerSelf organized, reliable and precise","datePosted":"2026-10-16T14:08:22.084Z","dateModified":"2026-10-16T14:08:22.084Z","hiringOrganization":{"@type":"Organization","name":"Intersources","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Denver","addressRegion":"CO","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"d2b6621bec8465d4117bcb79"},"url":"https://jobsearcher.com/jobs/d2b6621bec8465d4117bcb79"}}