{"schemaVersion":"jobsearcher.job.v1","id":"d1ed75a08114d9e9fe3b7229","url":"https://jobsearcher.com/jobs/d1ed75a08114d9e9fe3b7229","canonicalUrl":"https://jobsearcher.com/jobs/d1ed75a08114d9e9fe3b7229","title":"Principal Statistical Programmer","description":"Overview Cytel is shaping the future of drug development. As the world's largest independent clinical biostatistics research and development organization, we help leading pharmaceutical, biotech and medical device companies improve clinical success rates via optimal study design, effective data management, accurate statistical analysis and software. With operations across North America, Europe, and India, we are always on the lookout for passionate and talented people who share our mission of ensuring the clinical development of safe and effective medicines.\r\nWe are experiencing exponential growth on a global scale and hiring a Principal Statistical Programmer to join our PBS division. You will exercise your strong communication and leadership skills to support or lead one or more clinical trials, across various therapeutic areas. You will report to the Director, Statistical Programming.\r\nWhat You Will Contribute\r\nProviding significant technical expertise for statistical programming in all phases of programming support, developing automated reports and preparation of submission data standard packages.\r\nSupporting statistical programming activities for multiple and/or large/complex drug/vaccine clinical development projects.\r\nDevelopment and execution of statistical analysis and reporting deliverables (e.g. safety and efficacy analysis datasets, tables, listings, figures).\r\nDesign and maintenance of statistical datasets that support multiple stakeholder groups.\r\nServing as key collaborator with statistics and other project stakeholders in ensuring that project plans are executed efficiently with timely and high quality deliverables.\r\nBeing able to serve as statistical programming point of contact and knowledge holder through the entire product lifecycle for the assigned protocol if/when called upon.\r\nEffective analysis and report programming development and validation utilizing global and TA standards and following departmental SOPs and good programming practices.\r\nMaintaining and managing a project plan including resource forecasting.\r\nCoordinating the activities of the supplier's programming team; and interacting with client statistical programmers.\r\nUtilizing strong project management skills and ability to engage key stakeholders; leadership at a protocol level; determining approach and ensuring consistency, and directing development of others when opportunities arise.\r\nDesigning and developing complex programming algorithms.\r\nComprehending analysis plans which may describe methodology to be programmed; an understanding of statistical terminology and concepts.\r\nUtilizing expertise in CDISC and SDTM standards.\r\nStatistical programming for early and late stage clinical trials which can include both planned and ad-hoc needs.\r\nEnriched / Post Processed Datasets (individual or integrated).\r\nADaM datasets (individual or integrated).\r\nProtocol and therapeutic area specific tables, listings, and figures (individual or integrated).\r\nProgramming documentation following SOPs.\r\nWhat You Offer\r\nBachelor's degree or equivalent, preferably in a scientific discipline such as Statistics, Computer Science, Mathematics, etc.\r\n7-8 years of experience in biostatistics or statistical programming activities in the Pharmaceutical/Biotechnology industry in clinical development with good knowledge of CDISC ADaM and SDTM, ICH Statistical and Clinical Report Guidelines.\r\nStudy lead experience working with cross functional teams, including leading programming teams.\r\nStrong experience in QCing and validating work of other programmers, preferably outsourced work.\r\nStrong SAS data manipulation, analysis and reporting skills- with strong output programming experience.\r\nStrong proficiency implementing the latest CDISC SDTM / ADaM standards.\r\nFamiliarity with drug development life cycle and experience with the manipulation, analysis and reporting of clinical trials' data.\r\nSubmissions experience utilizing define.xml and other submission documents.\r\nExcellent analytical & troubleshooting skills.\r\nAbility to provide quality output and deliverables, in adherence with challenging timelines.\r\nAbility to work effectively and successfully in a globally dispersed team environment with cross-cultural partners.\r\nWhy Cytel?\r\nOur collaborative working environment encourages innovation and rewards results, and we are proud to have one of the lowest turnover rates in the industry.\r\nIn addition to a competitive compensation, we offer an excellent benefit's package, annual bonus incentive, promote work-life balance, and the opportunity to grow with us!\r\nWork with respected experts and thought leaders in the fields of biostatistics and statistical programming.\r\nCytel Inc. is an Equal Employment / Affirmative Action Employer. Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.\r\nCytel does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Cytel's human resources department to obtain prior written authorization before referring any candidates to Cytel. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and Cytel. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of Cytel. Cytel shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies.\r\nJ-18808-Ljbffr","company":"Research Computing Teams","rawCompany":"research computing teams","city":"California","state":"MO","isRemote":false,"isActive":false,"createdAt":"2026-08-07T00:51:20.833Z","occupations":[{"code":"15-2041.01","title":"Biostatisticians","slug":"biostatisticians"},{"code":"15-2041.00","title":"Statisticians","slug":"statisticians"},{"code":"15-2051.02","title":"Clinical Data Managers","slug":"clinical-data-managers"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"325412","title":"Pharmaceutical Preparation Manufacturing","slug":"pharmaceutical-preparation-manufacturing"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Principal Statistical Programmer","description":"Overview Cytel is shaping the future of drug development. As the world's largest independent clinical biostatistics research and development organization, we help leading pharmaceutical, biotech and medical device companies improve clinical success rates via optimal study design, effective data management, accurate statistical analysis and software. With operations across North America, Europe, and India, we are always on the lookout for passionate and talented people who share our mission of ensuring the clinical development of safe and effective medicines.\r\nWe are experiencing exponential growth on a global scale and hiring a Principal Statistical Programmer to join our PBS division. You will exercise your strong communication and leadership skills to support or lead one or more clinical trials, across various therapeutic areas. You will report to the Director, Statistical Programming.\r\nWhat You Will Contribute\r\nProviding significant technical expertise for statistical programming in all phases of programming support, developing automated reports and preparation of submission data standard packages.\r\nSupporting statistical programming activities for multiple and/or large/complex drug/vaccine clinical development projects.\r\nDevelopment and execution of statistical analysis and reporting deliverables (e.g. safety and efficacy analysis datasets, tables, listings, figures).\r\nDesign and maintenance of statistical datasets that support multiple stakeholder groups.\r\nServing as key collaborator with statistics and other project stakeholders in ensuring that project plans are executed efficiently with timely and high quality deliverables.\r\nBeing able to serve as statistical programming point of contact and knowledge holder through the entire product lifecycle for the assigned protocol if/when called upon.\r\nEffective analysis and report programming development and validation utilizing global and TA standards and following departmental SOPs and good programming practices.\r\nMaintaining and managing a project plan including resource forecasting.\r\nCoordinating the activities of the supplier's programming team; and interacting with client statistical programmers.\r\nUtilizing strong project management skills and ability to engage key stakeholders; leadership at a protocol level; determining approach and ensuring consistency, and directing development of others when opportunities arise.\r\nDesigning and developing complex programming algorithms.\r\nComprehending analysis plans which may describe methodology to be programmed; an understanding of statistical terminology and concepts.\r\nUtilizing expertise in CDISC and SDTM standards.\r\nStatistical programming for early and late stage clinical trials which can include both planned and ad-hoc needs.\r\nEnriched / Post Processed Datasets (individual or integrated).\r\nADaM datasets (individual or integrated).\r\nProtocol and therapeutic area specific tables, listings, and figures (individual or integrated).\r\nProgramming documentation following SOPs.\r\nWhat You Offer\r\nBachelor's degree or equivalent, preferably in a scientific discipline such as Statistics, Computer Science, Mathematics, etc.\r\n7-8 years of experience in biostatistics or statistical programming activities in the Pharmaceutical/Biotechnology industry in clinical development with good knowledge of CDISC ADaM and SDTM, ICH Statistical and Clinical Report Guidelines.\r\nStudy lead experience working with cross functional teams, including leading programming teams.\r\nStrong experience in QCing and validating work of other programmers, preferably outsourced work.\r\nStrong SAS data manipulation, analysis and reporting skills- with strong output programming experience.\r\nStrong proficiency implementing the latest CDISC SDTM / ADaM standards.\r\nFamiliarity with drug development life cycle and experience with the manipulation, analysis and reporting of clinical trials' data.\r\nSubmissions experience utilizing define.xml and other submission documents.\r\nExcellent analytical & troubleshooting skills.\r\nAbility to provide quality output and deliverables, in adherence with challenging timelines.\r\nAbility to work effectively and successfully in a globally dispersed team environment with cross-cultural partners.\r\nWhy Cytel?\r\nOur collaborative working environment encourages innovation and rewards results, and we are proud to have one of the lowest turnover rates in the industry.\r\nIn addition to a competitive compensation, we offer an excellent benefit's package, annual bonus incentive, promote work-life balance, and the opportunity to grow with us!\r\nWork with respected experts and thought leaders in the fields of biostatistics and statistical programming.\r\nCytel Inc. is an Equal Employment / Affirmative Action Employer. Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.\r\nCytel does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Cytel's human resources department to obtain prior written authorization before referring any candidates to Cytel. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and Cytel. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of Cytel. Cytel shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies.\r\nJ-18808-Ljbffr","datePosted":"2026-08-07T00:51:20.833Z","dateModified":"2026-08-07T00:51:20.833Z","hiringOrganization":{"@type":"Organization","name":"Research Computing Teams","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"California","addressRegion":"MO","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"d1ed75a08114d9e9fe3b7229"},"url":"https://jobsearcher.com/jobs/d1ed75a08114d9e9fe3b7229"}}