{"schemaVersion":"jobsearcher.job.v1","id":"ceff7d1af819c4fde0e8b7f7","url":"https://jobsearcher.com/jobs/ceff7d1af819c4fde0e8b7f7","canonicalUrl":"https://jobsearcher.com/jobs/ceff7d1af819c4fde0e8b7f7","title":"Machine Learning Scientist","description":"Machine Learning ScientistProfluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.\r\nWe're looking for a motivated and creative Machine Learning (ML) Scientist to drive research into new technologies for biomolecular design. This position offers an opportunity to work at the forefront of generative modeling research across language processing, representation learning, and protein engineering. You should be a self-directed researcher who has the ability to rapidly prototype and evaluate new models and algorithms in the biomolecular domain.\r\nAs an early employee, you will proactively shape the direction of our machine learning efforts and collaborate across diverse teams of computational and experimental scientists.\r\nResponsibilitiesDesign and develop state-of-the-art deep learning methods for protein sequence, structure, and function prediction and apply them to protein design\r\nCurate relevant datasets and design tasks for rigorous evaluation of generative models\r\nCollaborate with Biology team to design and characterize novel designed biomolecules\r\nImplement, analyze, and interpret multiple computational approaches and present results to colleagues in regular update meetings\r\nWork within a collaborative, fast-paced, interdisciplinary team across biology and machine learning to help shape the scientific and strategic vision of the company\r\nQualificationsPhD (or equivalent industry experience) in Computer Science, Machine Learning, Natural Language Processing, Applied Math, Computational Biology, Statistics, or a related field\r\nExperience with conceiving of, implementing, and evaluating novel machine learning techniques\r\nPublications at major machine learning conferences (NeurIPS, ICML, ICLR) or scientific journals (Nature, Science, Nature Biotech, Nature Methods, PNAS)\r\nExperience with modern deep learning frameworks such as Pytorch or Jax\r\nPreferences (but not required)Familiarity with foundational biology of proteins and nucleic acids\r\nExperience developing machine learning models for proteins (language models, structure prediction, design)\r\nPrevious experience in data extraction and curation from bioinformatics data sources\r\nFamiliarity with wet lab experimental assays and associated limitations\r\nExperience with cloud compute platforms (GCP, AWS, Azure)\r\nWhat We Offer At ProfluentA high-growth opportunity with meaningful impact\r\nCompetitive compensation package\r\nHealth insurance (health/dental/vision)\r\nGenerous paid time off (PTO) policy\r\nCommitment to physical and mental well-being\r\nMore benefits and perks to be added!\r\nProfluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.\r\nEmployment Eligibility Verification\r\nLegal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.\r\nHiring Salary Range\r\n$150,000 - $200,000 USD","company":"Profluent","rawCompany":"profluent","city":"Emeryville","state":"CA","isRemote":false,"isActive":false,"createdAt":"2026-04-09T08:30:26.180Z","occupations":[{"code":"15-2051.00","title":"Data Scientists","slug":"data-scientists"},{"code":"19-1029.01","title":"Bioinformatics Scientists","slug":"bioinformatics-scientists"},{"code":"15-1221.00","title":"Computer and Information Research Scientists","slug":"computer-and-information-research-scientists"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541990","title":"All Other Professional, Scientific, and Technical Services","slug":"all-other-professional-scientific-and-technical-services"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Machine Learning Scientist","description":"Machine Learning ScientistProfluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.\r\nWe're looking for a motivated and creative Machine Learning (ML) Scientist to drive research into new technologies for biomolecular design. This position offers an opportunity to work at the forefront of generative modeling research across language processing, representation learning, and protein engineering. You should be a self-directed researcher who has the ability to rapidly prototype and evaluate new models and algorithms in the biomolecular domain.\r\nAs an early employee, you will proactively shape the direction of our machine learning efforts and collaborate across diverse teams of computational and experimental scientists.\r\nResponsibilitiesDesign and develop state-of-the-art deep learning methods for protein sequence, structure, and function prediction and apply them to protein design\r\nCurate relevant datasets and design tasks for rigorous evaluation of generative models\r\nCollaborate with Biology team to design and characterize novel designed biomolecules\r\nImplement, analyze, and interpret multiple computational approaches and present results to colleagues in regular update meetings\r\nWork within a collaborative, fast-paced, interdisciplinary team across biology and machine learning to help shape the scientific and strategic vision of the company\r\nQualificationsPhD (or equivalent industry experience) in Computer Science, Machine Learning, Natural Language Processing, Applied Math, Computational Biology, Statistics, or a related field\r\nExperience with conceiving of, implementing, and evaluating novel machine learning techniques\r\nPublications at major machine learning conferences (NeurIPS, ICML, ICLR) or scientific journals (Nature, Science, Nature Biotech, Nature Methods, PNAS)\r\nExperience with modern deep learning frameworks such as Pytorch or Jax\r\nPreferences (but not required)Familiarity with foundational biology of proteins and nucleic acids\r\nExperience developing machine learning models for proteins (language models, structure prediction, design)\r\nPrevious experience in data extraction and curation from bioinformatics data sources\r\nFamiliarity with wet lab experimental assays and associated limitations\r\nExperience with cloud compute platforms (GCP, AWS, Azure)\r\nWhat We Offer At ProfluentA high-growth opportunity with meaningful impact\r\nCompetitive compensation package\r\nHealth insurance (health/dental/vision)\r\nGenerous paid time off (PTO) policy\r\nCommitment to physical and mental well-being\r\nMore benefits and perks to be added!\r\nProfluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.\r\nEmployment Eligibility Verification\r\nLegal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.\r\nHiring Salary Range\r\n$150,000 - $200,000 USD","datePosted":"2026-04-09T08:30:26.180Z","dateModified":"2026-04-09T08:30:26.180Z","hiringOrganization":{"@type":"Organization","name":"Profluent","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Emeryville","addressRegion":"CA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"ceff7d1af819c4fde0e8b7f7"},"url":"https://jobsearcher.com/jobs/ceff7d1af819c4fde0e8b7f7"}}