{"schemaVersion":"jobsearcher.job.v1","id":"cc54656473f6f8c1311b3c4f","url":"https://jobsearcher.com/jobs/cc54656473f6f8c1311b3c4f","canonicalUrl":"https://jobsearcher.com/jobs/cc54656473f6f8c1311b3c4f","title":"Fermentation Engineer II","description":"Fermentation Engineer II Augusta, Georgia, United States, Full-Time\nManus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self‑motivated and highly organized individual for a position that will specialize in and lead all laboratory operations at our Boston BioFacility.\n\nWe are seeking a Fermentation Engineer II to be a part of our process development team. This role focuses on fermentation science and development to bring new commercial bioprocesses through the Manus R&D pipeline. The Fermentation Engineer is responsible for the design, development, optimization, and scale‑up of microbial fermentation processes to produce bio‑alternatives, applying fundamental microbial physiology and fermentation science knowledge to achieve applied bioprocess objectives. This role bridges R&D and manufacturing, leading fermentation development from lab through pilot and commercial scales while ensuring robust, cost‑effective, and scalable operations.\n\nWhy work at Manus\n\nOpportunity – For motivated, results‑oriented team members, our growth creates opportunities for personal and professional advancement.\n\nAccountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.\n\nPassion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.\n\nOverview\nManus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.\n\nWe are seeking a Fermentation Engineer II or Senior Fermentation Engineer to be a part of our process development team. This role focuses on fermentation science and development to bring new commercial bioprocesses through the Manus R&D pipeline. The Fermentation Engineer is responsible for the design, development, optimization, and scale‑up of microbial fermentation processes to produce bio‑alternatives, applying fundamental microbial physiology and fermentation science knowledge to achieve applied bioprocess objectives. This role bridges R&D and manufacturing, leading fermentation development from lab through pilot and commercial scales while ensuring robust, cost‑effective, and scalable operations.\n\nThis hands‑on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus’s process development team located in Augusta, GA.\n\nResponsibilities\nProcess Development & Optimization\n\nDesign and optimize fermentation processes (batch, fed‑batch, continuous) for microbial or cell culture systems.\n\nDevelop strategies to improve yield, productivity, titer, and process robustness.\n\nConduct media optimization, feeding strategies, and metabolic performance analysis.\n\nApply statistical tools (DOE, multivariate analysis) to accelerate process improvement.\n\nScale‑Up & Technology Transfer\n\nLead fermentation scale‑up activities from laboratory (bench‑scale) to pilot and commercial manufacturing (e.g., 1 L – 4,000 L – 40,000 L).\n\nIdentify and mitigate scale‑dependent risks (mixing, oxygen transfer, heat removal, shear sensitivity).Support technology transfer to manufacturing sites or CMOs.\n\nDevelop scale‑down models to troubleshoot commercial process deviations.\n\nProcess Characterization & Validation\n\nDefine critical process parameters (CPPs) and critical quality attributes (CQAs).\n\nSupport process characterization studies and regulatory submissions (as applicable).\n\nDevelop control strategies for consistent production performance.\n\nData Analysis & Digital Tools\n\nAnalyze process data using advanced analytics, modeling, and visualization tools.\n\nDevelop predictive models for fermentation performance and scale‑up.\n\nImplement digital tools (PAT, soft sensors, automation strategies) to improve process control.\n\nLeadership & Collaboration\n\nLead cross‑functional project teams involving strain engineering, downstream processing, and manufacturing.\n\nMentor junior engineers and scientists.\n\nCollaborate with external partners, equipment vendors, and academic collaborators.\n\nSafety & Compliance\n\nEnsure compliance with EHS, GMP (if applicable), and regulatory guidelines.\n\nDesign processes with safety, sustainability, and regulatory considerations in mind.\n\nBasic Qualifications\n\nPhD with 5+ years in Industrial Fermentation Sciences, Engineering or related field\n\nRequired Technical Expertise\n\nExpertise in bench and pilot‑scale fermentation process development\n\nExpertise in microbial physiology\n\nExperience statistical tools for media design\n\nCritical thinker with enthusiasm for deriving solutions to complex challenges\n\nPreferred Experience\n\nExperience in scale‑up of fermentation processes from lab‑scale to pilot plant and/or production‑scale\n\nExperience with analytical instrumentation (GC, LC)\n\nExperience with fermentation modeling\n\n#J-18808-Ljbffr","company":"Inscripta","rawCompany":"inscripta","city":"Augusta","state":"GA","isRemote":false,"isActive":true,"createdAt":"2026-06-24T03:17:33.857Z","occupations":[{"code":"17-2112.03","title":"Manufacturing Engineers","slug":"manufacturing-engineers"},{"code":"19-1022.00","title":"Microbiologists","slug":"microbiologists"},{"code":"19-1012.00","title":"Food Scientists and Technologists","slug":"food-scientists-and-technologists"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"325193","title":"Ethyl Alcohol Manufacturing","slug":"ethyl-alcohol-manufacturing"},{"code":"312120","title":"Breweries","slug":"breweries"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Fermentation Engineer II","description":"Fermentation Engineer II Augusta, Georgia, United States, Full-Time\nManus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self‑motivated and highly organized individual for a position that will specialize in and lead all laboratory operations at our Boston BioFacility.\n\nWe are seeking a Fermentation Engineer II to be a part of our process development team. This role focuses on fermentation science and development to bring new commercial bioprocesses through the Manus R&D pipeline. The Fermentation Engineer is responsible for the design, development, optimization, and scale‑up of microbial fermentation processes to produce bio‑alternatives, applying fundamental microbial physiology and fermentation science knowledge to achieve applied bioprocess objectives. This role bridges R&D and manufacturing, leading fermentation development from lab through pilot and commercial scales while ensuring robust, cost‑effective, and scalable operations.\n\nWhy work at Manus\n\nOpportunity – For motivated, results‑oriented team members, our growth creates opportunities for personal and professional advancement.\n\nAccountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.\n\nPassion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.\n\nOverview\nManus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.\n\nWe are seeking a Fermentation Engineer II or Senior Fermentation Engineer to be a part of our process development team. This role focuses on fermentation science and development to bring new commercial bioprocesses through the Manus R&D pipeline. The Fermentation Engineer is responsible for the design, development, optimization, and scale‑up of microbial fermentation processes to produce bio‑alternatives, applying fundamental microbial physiology and fermentation science knowledge to achieve applied bioprocess objectives. This role bridges R&D and manufacturing, leading fermentation development from lab through pilot and commercial scales while ensuring robust, cost‑effective, and scalable operations.\n\nThis hands‑on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus’s process development team located in Augusta, GA.\n\nResponsibilities\nProcess Development & Optimization\n\nDesign and optimize fermentation processes (batch, fed‑batch, continuous) for microbial or cell culture systems.\n\nDevelop strategies to improve yield, productivity, titer, and process robustness.\n\nConduct media optimization, feeding strategies, and metabolic performance analysis.\n\nApply statistical tools (DOE, multivariate analysis) to accelerate process improvement.\n\nScale‑Up & Technology Transfer\n\nLead fermentation scale‑up activities from laboratory (bench‑scale) to pilot and commercial manufacturing (e.g., 1 L – 4,000 L – 40,000 L).\n\nIdentify and mitigate scale‑dependent risks (mixing, oxygen transfer, heat removal, shear sensitivity).Support technology transfer to manufacturing sites or CMOs.\n\nDevelop scale‑down models to troubleshoot commercial process deviations.\n\nProcess Characterization & Validation\n\nDefine critical process parameters (CPPs) and critical quality attributes (CQAs).\n\nSupport process characterization studies and regulatory submissions (as applicable).\n\nDevelop control strategies for consistent production performance.\n\nData Analysis & Digital Tools\n\nAnalyze process data using advanced analytics, modeling, and visualization tools.\n\nDevelop predictive models for fermentation performance and scale‑up.\n\nImplement digital tools (PAT, soft sensors, automation strategies) to improve process control.\n\nLeadership & Collaboration\n\nLead cross‑functional project teams involving strain engineering, downstream processing, and manufacturing.\n\nMentor junior engineers and scientists.\n\nCollaborate with external partners, equipment vendors, and academic collaborators.\n\nSafety & Compliance\n\nEnsure compliance with EHS, GMP (if applicable), and regulatory guidelines.\n\nDesign processes with safety, sustainability, and regulatory considerations in mind.\n\nBasic Qualifications\n\nPhD with 5+ years in Industrial Fermentation Sciences, Engineering or related field\n\nRequired Technical Expertise\n\nExpertise in bench and pilot‑scale fermentation process development\n\nExpertise in microbial physiology\n\nExperience statistical tools for media design\n\nCritical thinker with enthusiasm for deriving solutions to complex challenges\n\nPreferred Experience\n\nExperience in scale‑up of fermentation processes from lab‑scale to pilot plant and/or production‑scale\n\nExperience with analytical instrumentation (GC, LC)\n\nExperience with fermentation modeling\n\n#J-18808-Ljbffr","datePosted":"2026-06-24T03:17:33.857Z","dateModified":"2026-06-24T03:17:33.857Z","hiringOrganization":{"@type":"Organization","name":"Inscripta","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Augusta","addressRegion":"GA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"cc54656473f6f8c1311b3c4f"},"url":"https://jobsearcher.com/jobs/cc54656473f6f8c1311b3c4f"}}