{"schemaVersion":"jobsearcher.job.v1","id":"cc3abf5b486faab53196ffb2","url":"https://jobsearcher.com/jobs/cc3abf5b486faab53196ffb2","canonicalUrl":"https://jobsearcher.com/jobs/cc3abf5b486faab53196ffb2","title":"Senior Cryogenic Systems Engineer","description":"Until is a moonshot company building a “pause button” for biology. Our near‑term focus is organ‑scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole‑body reversible cryopreservation, giving patients a bridge to future cures.\n\nTo achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.\n\nWe envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.\n\nAbout the Role\nAs a Cryogenic Process & Systems Engineer at Until, you’ll lead design and execution of high‑pressure cryogenic fluid systems that support our perfusion and rewarming hardware. You’ll translate process requirements into engineered systems—pumps, piping, heat‑exchangers, instrumentation, and safety infrastructure—to enable organ‑scale vitrification and rewarming.\n\nYou’ll work side‑by‑side with mechanical engineers, materials scientists, and biologists to build, test, and iterate hardware that pushes the boundaries of cryogenic processing.\n\nWhat You’ll Do\n\nDesign, build, and validate cryogenic fluid systems including high‑pressure piping, pumps/compressors, valves, manifolds, instrumentation, and insulation.\n\nCreate and maintain process documentation (PFDs, P&IDs), system architecture drawings, and simulation/analysis of thermal/fluid/structural performance.\n\nSize and select cryogenic and high‑pressure equipment, coordinate integration, commissioning, and test of prototypes.\n\nPerform analyses of pressure drop, NPSH, fluid/thermal behavior, material embrittlement, heat in‑leak, and boil‑off dynamics.\n\nLead safety architecture for cryogenic systems: relief/vent systems, purging strategies, instrumentation, code compliance (ASME/API/NFPA/CGA).\n\nDevelop and run hardware test rigs, collect data, investigate failures, iterate rapidly.\n\nCollaborate with cross‑functional teams (mechanical, thermal, materials, biology) to integrate cryogenic hardware into larger systems.\n\nAbout You\n\nBachelor’s degree in Mechanical, Chemical, Petroleum or related Engineering discipline.\n\nAt least 3 years of experience working in one or more of these areas: LNG/liquid‑gas processing, cryogenic fluids (LN₂/LNG/LOX/LH₂), or high‑pressure industrial gas systems.\n\nHands‑on experience with high‑pressure piping, rotating equipment (pumps/compressors), valves and instrumentation in cryogenic or industrial‑gas contexts.\n\nStrong foundation in fluid mechanics, thermodynamics, heat‑transfer, material behavior at low temperature / high pressure.\n\nComfortable working in a hardware lab environment with prototype development and test.\n\nBonus points if you have experience with flow‑through or perfusive cooling architectures, process simulation tools (Aspen HYSYS/ProMax), HAZOPs or safety reviews, commissioning or vendor/EPC coordination, or prior work in LNG, industrial gases, aerospace cryogenics, or advanced cooling systems.\n\nBenefits\n\nA mission‑driven environment tackling one of the hardest problems in medicine.\n\nThe opportunity to build and direct a world‑class imaging program from the ground up.\n\nA deeply interdisciplinary team of scientists, engineers, and builders.\n\nGenerous medical, dental and vision insurance coverage\n\nFlexible time off and paid holidays\n\nCompetitive compensation package, including salary and equity\n\nAccess to a 401(k) retirement savings plan\n\nFSA and commuter benefits\n\nSubsidized lunch daily\n\nCompensation\n$140,000 - $175,000 a year\n\nWhile this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.\n\nAs an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.\n\n#J-18808-Ljbffr","company":"Until Labs","rawCompany":"until labs","city":"Millbrae","state":"CA","isRemote":false,"isActive":false,"createdAt":"2026-06-20T04:38:58.267Z","occupations":[{"code":"17-2199.00","title":"Engineers, All Other","slug":"engineers-all-other"},{"code":"17-2141.00","title":"Mechanical Engineers","slug":"mechanical-engineers"},{"code":"17-2031.00","title":"Bioengineers and Biomedical Engineers","slug":"bioengineers-and-biomedical-engineers"}],"industries":[{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"325120","title":"Industrial Gas Manufacturing","slug":"industrial-gas-manufacturing"},{"code":"333415","title":"Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment Manufacturing","slug":"air-conditioning-and-warm-air-heating-equipment-and-commercial-and-industrial-refrigeration-equipment-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Senior Cryogenic Systems Engineer","description":"Until is a moonshot company building a “pause button” for biology. Our near‑term focus is organ‑scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole‑body reversible cryopreservation, giving patients a bridge to future cures.\n\nTo achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.\n\nWe envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.\n\nAbout the Role\nAs a Cryogenic Process & Systems Engineer at Until, you’ll lead design and execution of high‑pressure cryogenic fluid systems that support our perfusion and rewarming hardware. You’ll translate process requirements into engineered systems—pumps, piping, heat‑exchangers, instrumentation, and safety infrastructure—to enable organ‑scale vitrification and rewarming.\n\nYou’ll work side‑by‑side with mechanical engineers, materials scientists, and biologists to build, test, and iterate hardware that pushes the boundaries of cryogenic processing.\n\nWhat You’ll Do\n\nDesign, build, and validate cryogenic fluid systems including high‑pressure piping, pumps/compressors, valves, manifolds, instrumentation, and insulation.\n\nCreate and maintain process documentation (PFDs, P&IDs), system architecture drawings, and simulation/analysis of thermal/fluid/structural performance.\n\nSize and select cryogenic and high‑pressure equipment, coordinate integration, commissioning, and test of prototypes.\n\nPerform analyses of pressure drop, NPSH, fluid/thermal behavior, material embrittlement, heat in‑leak, and boil‑off dynamics.\n\nLead safety architecture for cryogenic systems: relief/vent systems, purging strategies, instrumentation, code compliance (ASME/API/NFPA/CGA).\n\nDevelop and run hardware test rigs, collect data, investigate failures, iterate rapidly.\n\nCollaborate with cross‑functional teams (mechanical, thermal, materials, biology) to integrate cryogenic hardware into larger systems.\n\nAbout You\n\nBachelor’s degree in Mechanical, Chemical, Petroleum or related Engineering discipline.\n\nAt least 3 years of experience working in one or more of these areas: LNG/liquid‑gas processing, cryogenic fluids (LN₂/LNG/LOX/LH₂), or high‑pressure industrial gas systems.\n\nHands‑on experience with high‑pressure piping, rotating equipment (pumps/compressors), valves and instrumentation in cryogenic or industrial‑gas contexts.\n\nStrong foundation in fluid mechanics, thermodynamics, heat‑transfer, material behavior at low temperature / high pressure.\n\nComfortable working in a hardware lab environment with prototype development and test.\n\nBonus points if you have experience with flow‑through or perfusive cooling architectures, process simulation tools (Aspen HYSYS/ProMax), HAZOPs or safety reviews, commissioning or vendor/EPC coordination, or prior work in LNG, industrial gases, aerospace cryogenics, or advanced cooling systems.\n\nBenefits\n\nA mission‑driven environment tackling one of the hardest problems in medicine.\n\nThe opportunity to build and direct a world‑class imaging program from the ground up.\n\nA deeply interdisciplinary team of scientists, engineers, and builders.\n\nGenerous medical, dental and vision insurance coverage\n\nFlexible time off and paid holidays\n\nCompetitive compensation package, including salary and equity\n\nAccess to a 401(k) retirement savings plan\n\nFSA and commuter benefits\n\nSubsidized lunch daily\n\nCompensation\n$140,000 - $175,000 a year\n\nWhile this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.\n\nAs an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.\n\n#J-18808-Ljbffr","datePosted":"2026-06-20T04:38:58.267Z","dateModified":"2026-06-20T04:38:58.267Z","hiringOrganization":{"@type":"Organization","name":"Until Labs","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Millbrae","addressRegion":"CA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"cc3abf5b486faab53196ffb2"},"url":"https://jobsearcher.com/jobs/cc3abf5b486faab53196ffb2"}}