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Expertise in medicinal chemistry principles, cheminformatics, ADME, ML/AI and structure-based drug discovery. Expert proficiency in one or more commercial drug discovery platform such as ICM, Schrödinger, CCG and/or OpenEye.
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Expert proficiency in one or more commercial drug discovery platform such as ICM, Schrodinger, CCG and/or OpenEye. This vital Computer-Aided Drug Discovery (CADD) role, located at our Emeryville, CA site, will join our talented and innovative drug discovery team.
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We are seeking a Discovery Program Leader (DPL) to represent Nonclinical Drug Safety (NDS) on discovery research teams and in scientific and strategic review meetings focused primarily on immunology and oncology.
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The successful candidate will be responsible for the design, execution, and interpretation of mid/high throughput in vitro/ex vivo assays and mechanistic experimentation to advance early drug discovery projects from target concept through lead optimization.
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This is a highly dynamic and collaborative institute, working to apply disease agnostic technology such as proteomics and functional genomics, as well as biochemistry, computational biology, bioinformatics, and drug development to unravel the molecular networks underpinning host-pathogen interactions and developing targeted therapeutics.
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In this lab-based role, you will utilize your knowledge of protein chemistry and expertise in chromatography and capillary electrophoresis to contribute to development of AbbVie’s growing pipeline of clinical stage biotherapeutics, which include novel bispecific constructs, antibody-drug conjugates, and monoclonal antibodies.
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The Staff Scientist will be working with various discovery teams (DMPK, vivarium, chemistry, biology). The role of staff scientist within the formulation group is to support preclinical studies for discovery projects as well as formulation development for clinical phases as needed.
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Reporting to the Oncology Discovery Therapeutic Area head, you will partner with data science and machine learning (DSML), translational oncology and computational biology colleagues to gain deep insights into the biology and efficacy of antibody drug conjugates (ADCs) with the goal of delivering therapeutics to the right patients.
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The Scientist will engage in innovative research in a dynamic team environment with a focus on developing and executing in vivo and in vitro evaluations to support target validation and drug discovery efforts for advancement into human clinical trials.
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The Discovery AKTA Field Application Specialist for Cytiva is responsible for providing product & application support, and driving sales for lab AKTA instruments and lab resin. This position is part of the Discovery Commercial organization and will be fully remote requiring travel to customer sites and business meetings.
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The Principal Scientist will be Subject Matter Expert who will apply innovative Quantitative Clinical Pharmacology approaches to guide optimal drug development including. Experience in leading the design and implementation of clinical pharmacology and biopharmaceutic studies including bioequivalence, bio-comparability, drug-drug interaction, special population, ethnic sensitivity, ADME and pediatric studies and integrating results into regulatory filings, and product labels.
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Provide leadership to early-stage clinical scientists on the clinical study team for Early Clinical Development, working in a matrix team environment with other clinicians, statisticians, clinical pharmacologists, translational biologists, drug safety/pharmacovigilance, clinical supply, and regulatory specialists.
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Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years.
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Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery to select patient populations most likely to benefit from the therapies we are developing.
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Work collaboratively and proactively with colleagues in automation, computational biology, NGS and discovery in a matrixed team structure. We are seeking an outstanding Senior Scientist to lead immunology discovery efforts to develop next generation CAR T cellular therapies for cancer.
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nih drug discovery jobs Title: post doctoral fellow Company: Emory University in San Francisco, CA
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